alexa Dubious Action of Atrazine as an Endocrine Disrupting A

Journal of Cancer Clinical Trials
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Research Article

Dubious Action of Atrazine as an Endocrine Disrupting Agent: An In silico Approach

Shailima Rampogu1*, R.D. Neelima Vardhani2, SSNP Ekke3 and Rajesh Goud Gajula4

1Department of Biochemistry, Celesta Labs, Yousufguda, Hyderabad, Telangana, India

2TS Model School, Vennached (Village), Gandeed (Mandal), Mahabubnagar, India

3Department of BiGCaT (Bioinformatics), Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands

4Primer Biotech Research Center, Hyderabad, Telangana, India

*Corresponding Author:
Shailima Rampogu
Department of Biochemistry, Celesta Labs
Yousufguda, Hyderabad, Telangana, India
Tel: +918123211795
E-mail: [email protected]

Received date: May 04, 2017; Accepted date: May 20, 2017; Published date: May 30, 2017

Citation: Rampogu S, Vardhani N, SSNP Ekke, RG Gajula (2017) Dubious Action of Atrazine as an Endocrine Disrupting Agent: An In silico Approach. J Cancer Clin Trials 2:132.

Copyright: © 2017 Rampogu S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Atrazine is chlorine containing chemical compound which is widely used as an herbicide. However, upon its entry into the human body, it is known to affect several organs and their functions. Additionally, atrazine also represses photosynthesis in plants and causes serious disorders in animals as well. One of the most challenging actions of atrazine is its action has an endocrine disruptor. The present article makes an effort to delineate on the binding affinity of the herbicide to two human hormone receptors, and also to understand its endocrine disrupting capability adapting the computational methods.

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