Early Experience with Lung Transplantation in Patients with Idiopathic Pulmonary Fibrosis
Department of Surgery, Division of Cardiothoracic Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
- *Corresponding Author:
- Iskander Al-Githmi, MD, FRCSC, FACS, FCCP
Department of Surgery
Division of Cardiothoracic Surgery
King Abdulaziz University Hospital
P.O. Box 80215, Jeddah, Saudi Arabia
E-mail: [email protected]
Received date: January 09, 2013; Accepted date: May 30, 2013; Published date: June 07, 2013
Citation: Al-Githmi I (2013) Early Experience with Lung Transplantation in Patients with Idiopathic Pulmonary Fibrosis. Surgery Curr Res 3:128. doi:10.4172/2161-1076.1000128
Copyright: © 2013 Al-Githmi I. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Lung transplant is a treatment option for idiopathic pulmonary fibrosis. The purpose of this study was to review the results of lung transplant in patients with idiopathic pulmonary fibrosis. Methods: Between November 2008 and October 2010, there were 11 patients who had lung transplant at our institution; 6 patients (55%) had single lung transplant for idiopathic pulmonary fibrosis. Clinical data were reviewed retrospectively. Follow-up was 4 years. Results: The 6 patients who received single lung transplant for idiopathic pulmonary fibrosis had no perioperative mortality; 1 patient died within 30 days of surgery because of multiple organ failure that resulted from sepsis, and 1 patient died at 14 months after surgery because of respiratory failure and bronchiolitis obliterans. The overall survival was 83% at 1 year, 67% at 2 years, and 67% at 4 years after transplant. Conclusions: Lung transplant is effective in reducing the risk of death and prolonging survival in patients with idiopathic pulmonary fibrosis.