Early Exposure to Mercuric Chloride or Methylmercury Alters Zebrafish Embryo (Danio rerio) Development
- *Corresponding Author:
- Said A.H. Hassan
Department of Anatomy and Embryology
Faculty of Veterinary Medicine
Suez Canal University, Ismailia EGYPT
E-mail: [email protected]
Received Date: November 06, 2014; Accepted Date: April 25, 2017; Published Date: May 02, 2017
Citation: Abbott LC, Moussa EAM, Carl TL, Cortez D, Clayton HL, et al. (2017) Indigenous Chicken Production System and Breeding Practice in Southern Tigray, North Ethiopia. Poult Fish Wildl Sci 5: 178. doi: 10.4172/2375-446X.1000178
Copyright: © 2017 Abbott LC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Environmental mercury contamination is ubiquitous and toxic to developing embryos. Zebra fish embryos (ZFEs) were exposed for 24 h to different concentrations of mercuric chloride or methyl mercury. Exposure to 100 μg/L methyl mercury and 1000 μg/L mercuric chloride resulted in 100% mortality. ZFEs exposed to 100 μg/L or higher mercuric chloride exhibited decreased body length, deformed tails and reduced eye volume. Using Proliferating Cell Nuclear Antigen (PCNA) immunohistochemistry assessment at 30 h post fertilization, we determined that exposure to mercuric chloride did not alter cell proliferation in the developing brain. These ZFE data were compared to results obtained with methyl mercury exposure; both compounds produced delayed toxicity and methyl mercury is more toxic than mercuric chloride at equal concentrations.