alexa EBV Infection Resulting in Aplastic Anemia: A Case Report and Literature Review
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

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Research Article

EBV Infection Resulting in Aplastic Anemia: A Case Report and Literature Review

Israa Khan1, Susumu Inoue3*, Rao Mushtaq2 and Nkechi Onwuzurike3

1Departments of Pediatrics, Hurley Children’s Hospital/Michigan State University, USA

2Departments of Combined Internal Medicine-Pediatrics, Hurley Children’s Hospital and Hurley Medical Center/Michigan State University, USA

3Department of Pediatric Hematology/Oncology, Hurley Children’s Hospital/Michigan State University, USA

*Corresponding Author:
Susumu Inoue
Departments of Pediatrics and Hematology/ Oncology
Hurley Children’s Hospital, USA
E-mail: [email protected]

Received date: May 24, 2013; Accepted date: June 04, 2013; Published date: June 08, 2013

Citation: Khan I, Inoue S, Mushtaq R, Onwuzurike N (2013) EBV Infection Resulting in Aplastic Anemia: A Case Report and Literature Review. J Blood Disord Transfus 4:141. doi: 10.4172/2155-9864.1000141

Copyright: © 2013 Khan I, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



We describe a three year old girl who developedconcurrent with reactivation of EBV infection. Literature review yielded a list of 23 cases of documented EBV infection with aplastic anemia. Though acyclovir was used as one of the treatment modality in many cases including ours, its effectiveness is unclear. It would be beneficial to develop EBV associated aplastic anemia registry to prospectively evaluate Acyclovir’s effectiveness. Also evaluation for evidence of EBV infection in all cases of idiopathic aplastic anemia would be useful.

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