alexa Effect of Eyewash Solution (Commercial Washing Solution) on the Corneal Epithelium: Adverse Effects of Benzalkonium Chloride on the Eye Surface
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Effect of Eyewash Solution (Commercial Washing Solution) on the Corneal Epithelium: Adverse Effects of Benzalkonium Chloride on the Eye Surface

Masanori Iwashita1,2, Dogru Murato3, Hiroko Yano4, Yasuko Santo4, Manabu Nozaki4 and Hiroshi Fujishima1,2*

1Department of Ophthalmology, School of Dental Medicine, Tsurumi University, Kanagawa, Japan

2Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan

3Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan

4Kobayashi Pharmaceutical Co., Ltd, Osaka, Japan

*Corresponding Author:
Hiroshi Fujishima
Department of Ophthalmology
Tsurumi University School of Dental Medicine
2-1-3 Tsurumi, Tsurumi-ku
Yokohama, Kanagawa 230-8501, Japan
Tel: +81-45-581-1001
Fax: +81-45-573-9599
E-mail: [email protected]

Received date: May 09, 2016; Accepted date: June 24, 2016; Published date: June 28, 2016

Citation: Iwashita M, Murato D, Yano H, Santo Y, Nozaki M, et al. (2016) Effect of Eyewash Solution (Commercial Washing Solution) on the Corneal Epithelium: Adverse Effects of Benzalkonium Chloride on the Eye Surface. J Clin Exp Ophthalmol 7:571. doi:10.4172/2155-9570.1000571

Copyright: © 2016 Iwashita M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Purpose: In recent years, there has been an increasing interest in eye washing in healthy individuals due to pollinosis and an increase in the number of people wearing contact lenses. Previously, commercial eyewash solutions contained a preservative (benzalkonium chloride [BAK]) that was shown to be associated with epithelium disorders. However, currently, a reduction in corneal epithelium disorders is assumed to be due to the popularization of eyewash solutions lacking BAK (over-the counter drugs). Methods: We performed a comparative study between current eyewash solutions and those utilized in the past, and examined the effects of BAK on the cornea in both rabbit and human eyes. Results: Eyewash solutions containing BAK were associated with corneal epithelium disorders and collapse of the mucin layer in the cornea. However, eyewash solutions lacking BAK were not associated with corneal epithelium disorders and did not affect the mucin layer. Conclusion: The study highlights the adverse effects of a preservative and the safety of eyewash solutions not containing a preservative.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords