alexa Effect of Thylakoid Supplementation on Activities of Glucose Metabolizing Enzymes in Rats

Journal of Nutrition & Weight Loss
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Effect of Thylakoid Supplementation on Activities of Glucose Metabolizing Enzymes in Rats

Daisy Masih, Gurseen Rakhra and Som Nath Singh*

Nutrition Division, Defence Institute of Physiology and Allied Sciences (DIPAS), DRDO, Lucknow Road, Timarpur, Delhi-110054, India

Corresponding Author:
Som Nath Singh
Nutrition division, Defence Institute of Physiology and Allied Sciences (DIPAS)
DRDO, Lucknow Road, Timarpur, Delhi-110054, India
Tel: +91-11-23883315; 09811664006
Fax: 91-11-23914790
E-mail: [email protected]

Received Date: October 21, 2015; Accepted Date: February 02, 2016; Published Date: February 15, 2016

Citation: Masih D, Rakhra G, Singh SN (2016) Effect of Thylakoid Supplementation on Activities of Glucose Metabolizing Enzymes in Rats. Adv Weigh Loss Manag Med Dev 1:101. doi:10.4172/awmd.1000101

Copyright: © 2016 Masih D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Background and aims: Thylakoids are the photosynthetic sites present in the green plant cell which acts as appetite suppressant resulting in loss of body weight and enhancing satiety in animals and humans. The aim of present study was to investigate the effect of thylakoids on body weight gain and enzymatic activity of certain enzymes of glucose metabolism.

Methods:Thylakoids from spinach leaves were isolated and freeze dried. Supplementation of spinach thylakoids to Sprague dawley male rats (n=6) at an oral dose of 0.5 g/kg body weight for 4 days was carried out. Food intake, changes in body weight of treated and control rats were monitored and enzymatic activities in liver and muscle tissues were estimated at the end of the experiments.

Results: The gain in body weight was less in treated rats in comparison with control (control 12.1 g and treated 9.6 g, p<0.05). There was a significant increase (p<0.001) in specific activities of glucose 6-phosphate dehydrogenase (control vs. treated, liver: 6 times; muscles: 11.1 times), lactate dehydrogenase (control vs. treated, liver: 5.9 times; muscles: 6.8 times), succinate dehydrogenase (control vs. treated, liver: 1.5 times; muscle: 2.5 times) and malate dehydrogenase (control vs. treated, liver: 1.4 times; muscle: 5 times).

Conclusion: Dietary intake of spinach thylakoids increase the activity of glucose metabolizing enzymes, which indicates increased utilization of substrates for energy production in addition to regulate body weight gain in rats. This may be responsible for observed beneficial effects of thylakoid supplementation.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords