alexa Effect of Tunnel Structure of and#946;-TCP on Periodontal Repair in Class III Furcation Defects in Dogs | OMICS International | Abstract
ISSN:2090-5025

Bioceramics Development and Applications
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Research Article

Effect of Tunnel Structure of β-TCP on Periodontal Repair in Class III Furcation Defects in Dogs

Akira Saito1*, Emiko Saito2, Yasuo Ueda1, Yoshihiro Shibukawa3, Yoshiyuki Honma4, Tomomi Takahashi4, Mariko Kimura5, Yoshinori Kuboki6 and Hiroshi kato7

1Department of Oral Rehabilitation, Division of Oral Functional Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

2Departments of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

3Shibukawa Dental Clinics, Asahikawa, Japan.

4Support Section for Education and Research, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

5PILOT corporation, Hiratsuka, Japan.

6Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

7Kato Dental Clinic, Mito, Japan

*Corresponding Author :
Akira Saito, DDS, PhD
Department of Oral Rehabilitation
Division of Oral Functional Science
Hokkaido University Graduate School of Dental Medicine Kita-13
Nishi-7, Kita-ku, Sapporo 060-8586, Japan
Tel: +81 11 706 4275
Fax: +81 11 706 4276
E-mail: [email protected]

Received Date: Decenber 02, 2013; Accepted Date: January 16, 2014; Published Date: January 23, 2014

Citation: Saito A, Saito E, Ueda Y, Shibukawa Y, Honma Y, et al. (2014) Effect of Tunnel Structure of β-TCP on Periodontal Repair in Class III Furcation Defects in Dogs. Bioceram Dev Appl 4:073. doi:10.4172/2090-5025.1000073

Copyright: © 2014 Saito A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: The pore characteristics of bone graft materials play an important role in bone regeneration. Previous studies have reported that a pore size of 100 ~ 400 μm effectively induces vascular invasion and cell population within the materials. Many graft materials used recently have macropore (200 ~ 600 μm) or micropore (0.1 ~ 1 μm) structures. We devised a bone material with a tunnel pipe structure and pore size of 300 μm. The present study evaluated periodontal healing following implantation of this new bone graft material in furcation class III defects. Methods: Thirty mandibular premolar teeth of five beagles were used. After class III furcation defects were surgically created, each furcation was randomly treated with: 1) β-TCP with a tunnel pipe structure (tunnel group) (n=10); 2) Granular β-TCP (granular group) (n=10); and 3) No implant material (control group) (n=10). The dogs were sacrificed 8 weeks post-surgery and healing was evaluated histologically. Results: In the tunnel group, down growth of junctional epithelium was significantly less than that in the other two groups (P <0.01) and bone formation and blood capillary invasion were observed in the inner part of pores of the implanted material in the furcation. However, little bone formation was observed between the granules in the granular group. Conclusion: β- TCP with a tunnel pipe structure and pore size of 300 μm promotes bone regeneration and new cementum formation in class III furcation defects.

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