alexa Effectiveness Collagenase Injection in the Treatment of Patients with Dupuytren Systematic Review
ISSN: 2167-1222

Journal of Trauma & Treatment
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Review Article

Effectiveness Collagenase Injection in the Treatment of Patients with Dupuytren Systematic Review

Cobo-Molinos Jesús1* and Cobo-Molinos Antonio2

1Neurotraumatológico Hospital Complex of Jaén, Spain

2Department of Health Sciences, University of Jaen, Hospital of Jaen, Spain

*Corresponding Author:
Cobo-Molinos Jesús
Neurotraumatológico Hospital Complex of Jaén, Spain
Tel: +34953212121
E-mail: [email protected]

Received date: October 14, 2016; Accepted date: November 05, 2016; Published date: November 07, 2016

Citation: Jesús CM, Antonio CM (2016) Effectiveness Collagenase Injection in the Treatment of Patients with Dupuytren Systematic Review. J Trauma Treat 5:343. doi:10.4172/2167-1222.1000343

Copyright: © 2016 Jesús CM, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Objetive: The purpose of this systematic review was to examine the scientific evidence found to determinate the effectiveness of collagenase injection in the treatment of Dupuytren´s contracture. Materials and methods: It was done through a literature search in 3 databases: PubMed, Scopus and PEDro. It was located 102 studies but only 8 clinical trial were selected because they fulfilled the criteria of inclusion and exclusion. Every clinical trial was assessed with PEDro scale. Results: In the 8 studies had a significant improvement of contracture in the patients who had an injection collagenase. The improvement is similar to proximal interphalangeal joint to Metacarpophalangeal joints. Conclusions: Despite the lack of studies about the effectiveness of this new treatment method, based on the chosen for our study we can say that the technique of collagenase can be effective in reducing the contracture caused by Dupuytren's disease.


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