Effectiveness Collagenase Injection in the Treatment of Patients with Dupuytren Systematic ReviewCobo-Molinos Jesús1* and Cobo-Molinos Antonio2
- *Corresponding Author:
- Cobo-Molinos JesÃºs
NeurotraumatolÃ³gico Hospital Complex of JaÃ©n, Spain
E-mail: [email protected]
Received date: October 14, 2016; Accepted date: November 05, 2016; Published date: November 07, 2016
Citation: JesÃºs CM, Antonio CM (2016) Effectiveness Collagenase Injection in the Treatment of Patients with Dupuytren Systematic Review. J Trauma Treat 5:343. doi:10.4172/2167-1222.1000343
Copyright: © 2016 JesÃºs CM, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objetive: The purpose of this systematic review was to examine the scientific evidence found to determinate the effectiveness of collagenase injection in the treatment of DupuytrenÂ´s contracture. Materials and methods: It was done through a literature search in 3 databases: PubMed, Scopus and PEDro. It was located 102 studies but only 8 clinical trial were selected because they fulfilled the criteria of inclusion and exclusion. Every clinical trial was assessed with PEDro scale. Results: In the 8 studies had a significant improvement of contracture in the patients who had an injection collagenase. The improvement is similar to proximal interphalangeal joint to Metacarpophalangeal joints. Conclusions: Despite the lack of studies about the effectiveness of this new treatment method, based on the chosen for our study we can say that the technique of collagenase can be effective in reducing the contracture caused by Dupuytren's disease.