alexa Effectiveness of Insulin Pump Therapy in a Patient with Familial Partial Lipodystrophy of Dunnigan Type
ISSN: 2155-6156

Journal of Diabetes & Metabolism
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Case Report

Effectiveness of Insulin Pump Therapy in a Patient with Familial Partial Lipodystrophy of Dunnigan Type

Katarzyna Nabrdalik1*, Edyta Cichocka1, Wojciech Fendler2, Wojciech Mlynarski2 and Janusz Gumprecht1

1Department of Internal Medicine, Diabetology and Nephrology, Medical University of Silesia, Katowice, Poland

2Department of Paediatrics, Oncology, Hematology and Diabetology, Medical University of Lódz, Poland

*Corresponding Author:
Katarzyna Nabrdalik
Department of Internal Medicine
Diabetology and Nephrology
Medical University of Silesia
3 Maja 13-15, 41-800 Zabrze, Poland
Tel: +48 323704415
Fax: +48 32 271 46 17
E-mail: [email protected]

Received date: June 04, 2014; Accepted date: June 27, 2014; Published date: July 04, 2014

Citation: Nabrdalik K, Cichocka E, Fendler W, Mlynarski W, Gumprecht J (2014) Effectiveness of Insulin Pump Therapy in a Patient with Familial Partial Lipodystrophy of Dunnigan Type. J Diabetes Metab 5:404. doi:10.4172/2155-6156.1000404

Copyright: © 2014 Nabrdalik K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Familial Partial Lipodystrophy of the Dunnigan Type (FPLD) is a rare autosomal, dominant disorder where selective loss of subcutaneous adipose tissue from the limbs and trunk, accumulation of fat in the neck and face is usually associated with variety of metabolic disorders. In this report we present a case of 24-year-old Polish normal body weight woman with FLPD phenotype and genotype, concomitant poorly controlled diabetes mellitus and severe insulin resistance. As a preparation for pregnancy insulin pump therapy has been administrated instead of multi-day insulin injections which resulted in immediate extreme improvement in reduction of daily insulin dose and diabetes control. To our knowledge this is the first report on insulin pump therapy in a patient with FPLD that resulted in and unanticipated reduction in daily insulin dose and good diabetes control.


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