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Research Article

Effects Of A Novel Dental Gel On Plaque And Gingivitis: A Comparative Study

Dadkhah M1, Chung NE1, Ajdaharian J1, Wink C1,2, Klokkevold P3 and Wilder-Smith P1*

1Beckman Laser Institute, University of California, Irvine, California 92612, USA

2School of Dental Hygiene, Concorde Career College, Garden Grove, California 92840, USA

3School of Dentistry, Section of Periodontics, University of California, Los Angeles, California 90095, USA

*Corresponding Author:
Petra Wilder-Smith, DDS, PhD
Associate Professor and Director of Dentistry
Beckman Laser Institute, University of California at Irvine
1002 Health Sciences Rd East, Irvine, CA 92612, USA
Tel: 949-824-4713
Fax: 949-824-8413
E-mail: [email protected]

Received date: April 03, 2014; Accepted date: May 28, 2014; Published date: May 30, 2014

Citation: Dadkhah M, Chung NE, Ajdaharian J, Wink C, Klokkevold P, et al. (2014) Effects of a Novel Dental Gel on Plaque and Gingivitis: A Comparative Study. Dentistry 4:239. doi: 10.4172/2161-1122.1000239

Copyright: © 2014 Dadkhah M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objectives: The goal of this prospective, randomized, controlled, double-blinded study was to evaluate the effects of a novel dental gel on plaque and gingival health. The dental gel was designed to (1) break up and prevent re-accumulation of microbial biofilm, and (2) inhibit metal mediated inflammation.
Materials and Methods: Twenty-five subjects with moderate gingival inflammation (Löe and Silness Gingival Index ≥2) and pocket depths <4 were randomly assigned to brush twice daily for 21 days with the test or the control dental gel. On Days 0, 7, 14 and 21, plaque levels (Quigley-Hein, Turesky Modification Plaque Index), gingival inflammation (Löe and Silness Gingival Index) and gingival bleeding (modified Sulcus Bleeding Index) were determined by one blinded, investigator using a pressure sensitive probe.
After 3 weeks, all 3 clinical indices were significantly improved in both groups (P<0.05) and significantly lower in the test group (P<0.05).
Conclusion: The novel dental gel formulation was provided effective plaque control and reduced gingival inflammation.
Clinical Relevance: A novel dentifrice formulation may be an effective tool for plaque removal and maintaining gingival health.


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