alexa Effects of Delayed Release Microsphere of Exenatide on Peri-Implant Bone Response of Diabetic Rats
ISSN: 2161-1122

Dentistry
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication

Effects of Delayed Release Microsphere of Exenatide on Peri-Implant Bone Response of Diabetic Rats

Wenjuan Zhou1,2, Stefan Tangl4,5, Fei Chi2, Xilong Yue2, Shutai Liu2, Zhonghao Liu2 and Xiaohui Rausch-Fan1,3*

1Competent Center of Periodontal Research, Dental School of Medical University, Vienna, Austria

2Department of Dental Implantology, Affiliated Hospital of Stomatology of Yantai, Binzhou Medical University, Yantai, China

3Division of Conservative Dentistry and Periodontology, Dental School of Medical University, Vienna, Austria

4Division of Oral Surgery, Dental School of Medical University, Vienna, Austria

5Cluster for Tissue Regeneration, Vienna, Austria

*Corresponding Author:
Xiaohui Rausch-Fan
Professor, Competent Center of Periodontal Research
Division of Conservative Dentistry and Periodontology
Dental School of Medical University, Sensengasse 2a, 1090, Vienna, Austria
Tel: +43 / 1 / 40070-4748
Fax: +43 / 1 / 40070-4709
E-mail: [email protected]

Received date : August 23, 2015; Accepted date : September 03, 2015; Published date : September 14, 2015

Citation: Zhou W, Tangl S, Chi F, Yue X, Liu S, et al. (2015) Effects of Delayed Release Microsphere of Exenatide on Peri-Implant Bone Response of Diabetic Rats. Dentistry 5:335. doi:10.4172/2161-1122.1000335

Copyright: © 2015 Zhou W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



 

Abstract

Objectives: The aim of this study is to evaluate and compare the impact of delayed release microsphere of exenatide on dental implants treatment of diabetic rats.

Materials and methods: 6 male Zucker Diabetic Fatty (ZDF) rats were divided into three groups: GroupA, diabetic rats with dental implants (controls). Group B, diabetic rats treated with exenatide and implants placed simultaneously. Group C, diabetic rats treated with exenatide until serum glucose at a constant level and then implants were placed. Implants with surrounding bone tissues were harvested and bone responses were assessed by histomorphometric analysis.

Results: Osseointegration of all implants had proceeded, bone response to implant surface of one implant in group A was similar to that in group B and C, and implants were surrounded by dense, very compact bone, osteocytes were deposited in lamellar bone in group C.

Conclusion: The present study of dental implants with Diabetes mellitus suggested that the process of osseointegration is affected by diabetes, early osseointegration can be enhanced in individuals with well-controlled diabetes, but the included samples were too small to get a statistical conclusion, further well designed comparative studies are needed to explore the exact effect of diabetes and metabolic control on bone response to dental implants.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords