alexa Effects of Different Aerobic Exercise Programs with Nutritional Intervention in Primary Hypertensive and Overweight/Obese Adults: EXERDIET-HTA Controlled Trial
ISSN: 2167-0870

Journal of Clinical Trials
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Protocol

Effects of Different Aerobic Exercise Programs with Nutritional Intervention in Primary Hypertensive and Overweight/Obese Adults: EXERDIET-HTA Controlled Trial

Sara Maldonado-Martín1,2*, Ilargi Gorostegi-Anduaga1,2, Gualberto R Aispuru3, Maitane Illera-Villas4, Borja Jurio-Iriarte1,2, Silvia Francisco-Terreros5 and Javier Pérez-Asenjo6
1Department of Physical Education and Sport. Faculty of Education and Sport. University of the Basque Country (UPV/EHU). Vitoria-Gasteiz. Araba/Álava. Basque Country, Spain
2Nutrition, Exercise and Health Research Group. Elikadura, Ariketa Fisikoa eta Osasuna, ELIKOS group (UPV/EHU), Spain
3Hospital Santiago Apostol, Miranda de Ebro Burgos, Spain
4Department of Nutrition and Food Sciences. University of the Basque Country (UPV/EHU), Spain
5Clinical Trials Unit. Health and Quality of Life Area. TECNALIA. Vitoria-Gasteiz. Araba/Álava. Basque Country, Spain
6Cardiology Unit. Igualatorio Médico Quirúrgico (IMQ-Amárica). Vitoria-Gasteiz. Araba/Álava. Basque Country, Spain
Corresponding Author : Sara Maldonado-Martín
Department of Physical Education and Sport. Faculty
of Education and Sport. University of the Basque Country
(UPV/EHU). Portal de Lasarte, 71. 01007 Vitoria-Gasteiz
(Araba/Alava)-Basque Country, Spain
Tel: +34-945013534
Fax: +34-945013501
E-mail: [email protected]
Received: January 13, 2016 Accepted: February 15, 2016 Published: February 22, 2016
Citation: Maldonado-Martín S, Gorostegi-Anduaga I, Aispuru GR, Illera-Villas M, Jurio-Iriarte B, et al. (2016) Effects of Different Aerobic Exercise Programs with Nutritional Intervention in Primary Hypertensive and Overweight/Obese Adults: EXERDIET-HTA Controlled Trial. J Clin Trials 6:252. doi:10.4172/2167-0870.1000252
Copyright: © 2016 Maldonado-Martín S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Background: Both exercise training and diet are recommended to prevent and control primary hypertension (HTN) and overweight/obesity. Aerobic exercise is firmly established as an effective measure for lowering blood pressure (BP) and reducing cardiovascular risk. However, there is no agreement about the optimal dose of frequency, intensity, time and type of exercise. This study is a randomized control trial to investigate the effectiveness of different aerobic exercise programs and diet for reducing BP, for improving body composition, cardiorespiratory fitness, biochemical profile, physical activity and sedentary behavior and health-related quality of life in adults with primary HTN and overweight or obesity.
Methods/Design: One hundred sixty-four overweight or obese participants (18-70 yr old) diagnosed with primary HTN will perform different assessments to evaluate BP, physical, biochemical and nutritional condition, sedentary behavior and quality of life before and after 16-week of follow-up. All participants will receive an energy-hypocaloric diet based on 25% of measured resting metabolic rate and will be randomly assigned to control group (only diet) or exercise groups (diet plus aerobic exercise). Participants assigned to an exercise group will train 2 days/week under supervision (treadmill and bike protocol). There will be three aerobic exercise groups: (1) moderate continuous exercise and high volume (MCT) group, (2) high-intensity interval training and high-volume (HV-HIIT) group, and (3) high-intensity interval training and low-volume (LV-HIIT) group. The measurements used in the protocol will be taken before and after the intervention period (16-weeks), and after a six-month period in all participants (i.e., 6 months with only recommendations and no supervision).
Discussion: The results of this intervention will help to better understand the potential of non-pharmacological treatment for improving the well-being of people with primary HTN and overweight or obesity.

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