alexa Effects of Interdialytic Weight Gain on Lung Function T
ISSN: 2161-0940

Anatomy & Physiology: Current Research
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Research Article

Effects of Interdialytic Weight Gain on Lung Function Tests in Hemodialyzed Patients

Kovacevic P1,2*, Rajkovaca Z1, Jakovljevic B3, Kovacevic T4, Momcicevic D2 and Veljkovic S5

1Department of Physiology, School of Medicine, University of Banja Luka, Bosnia-Herzegovina

2Medical Intensive Care Unit, Clinical Centre Banja Luka, Bosnia - Herzegovina

3International Dialysis Centre Banja Luka, Bosnia - Herzegovina

4Department for hospital pharmacy, Clinical Centre Banja Luka, Bosnia - Herzegovina

5Institute for Physiology, Medical School Niš, Serbia

*Corresponding Author:
Kovacevic P
Department of Physiology, School of Medicine
University of Banja Luka, Bosnia-Herzegovina
Tel: +387 65 668 400
Fax: +387 51 281 400
E-mail: [email protected]

Received date: February 11, 2014; Accepted date: June 03, 2014; Published date: June 05, 2014

Citation: Kovacevic P, Rajkovaca Z, Jakovljevic B, Kovacevic T, Momcicevic D, et al. (2014) Effects of Interdialytic Weight Gain on Lung Function Tests in Hemodialyzed Patients. Anat Physiol 4:146. doi: 10.4172/2161-0940.1000146

Copyright: © 2014 Kovacevic P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Complications of respiratory system in patients suffering from chronic renal failure who are treated with regular haemodialysis are well known. However, the effects of interdialytic weight gain on respiratory function in these patients are less known. Hence, this study was designed with the aim to determine the potential differences in spirometry related to the different interdialytic weight gain.
The study included 32 patients, 16 males (50%) aged 51 (± 11), with ESRD who had been treated with repeated haemodialysis. The patients were divided into two groups: Group 1 – patients with interdialytic weight gain < 5% and Group 2 – patients with interdialytic weight gain > 5%. All patients had spiromety done before (A) and after (B) haemodialysis.
The results obtained show vital capacity means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.95 ± 0.9 and B=3.9 ± 1.2 and group 2: A=3.4 ± 1.1 and B=3.8 ± 1.12. Forced vital capacity means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.9 ± 0.85 and B=3.2 ± 1.0 and group 2: A=3.7 ± 1.4 and B=3.8 ± 1.35. Forced expiratory volume in first second means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.4 ± 0.78 and B=2.7 ± 1.1 and group 2: A=3.3 ± 1.25 and B=3.4 ± 1.33.
The results lead us to a conclusion that haemodialysis has a positive effect on pulmonary ventilating function, but this effect is smaller in patients with greater interdialytic weight gain.

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