alexa Effects of Lipofundin ® on the Measurement of Total Bilirubin by Spectrophotometry | OMICS International | Abstract
ISSN: 2157-7536

Journal of Steroids & Hormonal Science
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Effects of Lipofundin ® on the Measurement of Total Bilirubin by Spectrophotometry

Ju-Ting Hsueh 1 , Kwei-Shuai Hwang2 , Lu Pai3 , Yu-Lueng Shih4 , Jen-Jiuan Liaw5 , Shyi-Jou Chen6 , Shinn-Ying Ho7 and Hueng-Chuen Fan6 *

1Department of Family and Community Health, Tri-Service General Hospital, Taipei, Taiwan

2Department of Obstetrics and Gynecology, Tri-Service General Hospital, Taipei, Taiwan

3Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan

4Department of gastroenterology, Tri-Service General Hospital, Taipei, Taiwan

5School of nursing, National Defense Medical Center, Taipei, Taiwan

6Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan

7Institute of Bioinformatics and Systems Bology, National Chiao tung University, Hsinchu, Taiwan

*Corresponding Author:
Hueng-Chuen Fan, MD, PhD
Department of Pediatrics, Tri-Service General Hospital
National Defense Medical Center, No 325, Sec 2
Chenggong Rd, Neihu Dist, Taipei City 114, Taiwan
Tel: +886 2 87923311-13628
Fax: +886 2 87927293
E-mail: [email protected]

Received date: October 05, 2011; Accepted date: November 22, 2011; Published date: November 25, 2011

Citation: Hsueh JT, Hwang KS, Pai L, Shih YL, Liaw JJ, Chen SJ, et al. (2011) Effects of Lipofundin® on the Measurement of Total Bilirubin by Spectrophotometry. J Steroids Horm Sci 4:118. doi:10.4172/2157-7536.1000118

Copyright: © 2011 Hsueh JT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Jaundice occurs frequently in neonates and can cause severe neurological complications; hence, hyperbilirubinemia is usually monitored by direct spectrophotometry. However, lipemia, resulting from inborn disorders or parenteral feeding of preterm neonates with lipid emulsion, may interfere with certain laboratory assessments. Here, we evaluated whether artificial lipemia also interferes with bilirubin measurement by direct spectrophotometry. Methods: Total bilirubin levels were assessed by the spectrophotometry when serial concentrations of Lipofundin®, medium-chain triglycerides, or a stabilizer solution, were added to cord blood samples from five full-term and five preterm newborn infants. Results: In blood specimens from ten neonates, spectrophotometry-determined bilirubin levels proportionally and significantly increased in the presence of Lipofundin® at least 1% v/v or 10% medium-chain triglycerides at least 10% v/v in all pre-term and full-term infants. The stabilizer solution caused no interference. Conclusion: Lipofundin® in the cord blood interferes with spectrophotometric measurement of total bilirubin; this effect is mainly related to triglyceride levels and has implications for management of neonates with jaundice.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7