Effects of Supervised Short-Term Exercise Training On Cardiorespiratory Control and Exercise Capacity in Type 2 Diabetes PatientsTobias Duennwald1*, Hannes Gatterer1, Maria Wille1, Elena Pocecco1, Marc Philippe1, Philipp Kruesmann1, Alexander Dzien2,Luciano Bernardi3 and Martin Burtscher1
- *Corresponding Author:
- Tobias Dünnwald, PhD
Department of Sport Science, Medical Section
University of Innsbruck, 6020 Innsbruck, Austria
Tel: +43-512/507 54888
Fax: +43-512/507 54999
E-mail: [email protected]
Received date: July 14, 2014; Accepted date: August 26, 2014; Published date: September 03, 2014
Citation: Duennwald T, Gatterer H, Wille M, Pocecco E, Philippe M, et al. (2014) Effects of Supervised Short-Term Exercise Training On Cardiorespiratory Control and Exercise Capacity in Type 2 Diabetes Patients. J Diabetes Metab 5:418. doi: 10.4172/2155-6156.1000418
Copyright: © 2014 Duennwald T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective:Type 2 diabetes is associated with impaired respiratory and cardiovascular control. Physical exercise training is a well-established tool in the treatment of diabetes. However, effects of short-term exercise training on respiratory control in diabetes are unknown. Thus, we examined the effects of 4 weeks of exercise training (high intensity interval- and continuous moderate exercise training; HIT and CMT) on cardiorespiratory control and aerobic capacity in type 2 diabetes subjects.
Methods: Fifteen non-insulin dependent subjects with type 2 diabetes (4 female, 11 male, age 59.6 ± 1.5 years, BMI 29.5 ± 1.0 kg/m2, HbA1C 7.0 ± 0.3%) were randomized to either supervised HIT (N=8) or CMT (N= 7), both equalized for the total amount of work, for 3 times a week over 4 weeks. At baseline and follow up, measurements of hypercapnic and hypoxic ventilatory response (HCVR; HVR), Baroreflex Sensitivity (BRS) and VO2 peak were performed.
Results: Four weeks of supervised exercise training increased resting HCVR (from 0.55 ± 0.1 to 0.73 ± 0.1 L/ min/mmHgCO2-et), whereas HVR and BRS remained unchanged. VO2 peak (27.5 ± 1.4 versus 30.1 ± 1.6 ml/kg/min) and VO2 at anaerobic threshold (19.7 ± 1.0 versus 21.9 ± 1.3 ml/kg/min) increased in the whole group. No significant changes between HIT and CMT were observed, except a slight increase in haemoglobin concentration after HIT.
Conclusion: Our findings indicate that short-term exercise training increases HCVR associated with an improvement in aerobic capacity in patients with type 2 diabetes. HIT might demonstrate a less time demanding alternative to CMT. These findings are of clinical relevance, as exercise capacity predicts cardiovascular and overall mortality.