alexa Efficacy and Safety of Non-Invasive Ventilation for Post Extubation Respiratory Distress in Hypoxic and Hypercapnic Respiratory Failure | OMICS International | Abstract
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
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Research Article

Efficacy and Safety of Non-Invasive Ventilation for Post Extubation Respiratory Distress in Hypoxic and Hypercapnic Respiratory Failure

Alaa Mohammed Atia1*, Khaled Abdel-Baqy Abdel-Rahman1 and Khaled Ahmed Hussein2

1Department of Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Egypt

2Department of Chest, Faculty of Medicine, Assiut University, Egypt

*Corresponding Author:
Alaa M Atia
Department of Anesthesia and Intensive Care
Faculty of Medicine
Assiut University, Egypt
Tel: 0201223591937
E-mail: [email protected]

Received date: June 13, 2016; Accepted date: August 03, 2016; Published date: August 10, 2016

Citation: Atia AM, Abdel-Rahman KA, Hussein KA (2016) Efficacy and Safety of Non-Invasive Ventilation for Post Extubation Respiratory Distress in Hypoxic and Hypercapnic Respiratory Failure. J Anesth Clin Res 7:654. doi: 10.4172/2155-6148.1000654

Copyright: © 2016 Atia AM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Respiratory distress after extubation with the need for reintubation is a common event. The act of reintubation is associated with numerous life-threatening complication and high mortality rate. The role of noninvasive ventilation (NIV) in patients who developed respiratory distress is not clear.

Aim of the study: To assess the effectiveness of non-invasive pressure support ventilation (NIPPV) in avoiding reintubation in patients who develop respiratory distress after extubation in hypoxic and hypercapnic patients.

Patients and methods: In this prospective observational study, one hundred and three patients with post extubation respiratory distress met our inclusion and exclusion criteria and were enrolled. NIPPV were applied to all patients and they were monitored for signs of failure of this technique and the need for reintubation. This cohort is further divided according to the initial cause of respiratory failure into hypoxic and hypercapnic groups. The primary outcome measure was the technique success rate to avoid reintubation; secondary outcome measures were ICU mortality, length of ICU stay.

Results: No statistically significant differences were observed in success rate, mortality and length of ICU stay between both groups.

Conclusion: The type of respiratory failure as a primary etiology for mechanical ventilation does not affect the success rate of the use of NIPPV in patients who developed post extubation respiratory distress.


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