alexa Efficacy of High Carbohydrate versus High Protein Meal Replacements on Weight Reduction - A Randomized Controlled Trial | OMICS International | Abstract
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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Research Article

Efficacy of High Carbohydrate versus High Protein Meal Replacements on Weight Reduction - A Randomized Controlled Trial

Katharina Möller*, Janina Willers and Andreas Hahn
Institute of Food Science and Human Nutrition, Leibniz University Hannover, Germany
Corresponding Author : Katharina Möller
Leibniz University of Hannover
Institute of Food Science and Human Nutrition
Am Kleinen Felde 30, 30167 Hannover
Germany
Tel: +49 (0)511-762 3317
Fax: +49 (0)511-762 5729
E-mail: [email protected]
Received May 06, 2015; Accepted June 8, 2015; Published June 30, 2015
Citation: Möller K, Willers J, Hahn A (2015) Efficacy of High Carbohydrate Versus High Protein Meal Replacements on Weight Reduction-A Randomized Controlled Trial. J Obes Weight Loss Ther 5:266. doi:10.4172/2165-7904.1000266
Copyright: ©2015 Möller K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: While formula diets as meal replacements are evident for weight loss, the macronutrient composition is still in the focus of interest. This study was designed to determine effects of a carbohydrate-riched meal replacement on weight loss and waist circumferences (WC) in comparison with a protein-riched meal replacement. Methods: Two groups (high carbohydrate formula diet (HC) and high protein formula diet (HP)) of 80 matched subjects each underwent a randomized parallel intervention trial for eight weeks followed by a 12-week follow-up. The intervention consisted of three phases: (1) week 1 and 2: total replacement of three meals, (2) week 3 and 4: replacement of two meals and (3) week 5 to 8: replacement of one meal. Measurements were taken at week 0, 2, 8, and 20. Results: After two weeks of total meal replacement, there was a significant (p<0.001) weight loss in both groups (HC: -4.0 ± 4.7 kg vs. HP: -4.3 ± 1.8 kg). After eight weeks, 66.2% of all subjects achieved a weight loss of 5% and more (HC: -8.5 ± 2.5%, p<0.001 vs. HP: -8.8 ± 2.8%, p<0.001), and 18.2% of the participants lost more than 10% of their initial body weight. Waist circumferences decreased from 105.9 ± 9.7 cm to 97.4 ± 8.4 cm (p<0.001) after eight weeks. During the follow up, further weight loss was observed in both groups. There were no significant differences between the HC and HP-group regarding changes in weight and WC. Conclusion: Both dietary intervention strategies had a similar effect on weight loss and WC reduction. In this short-term study macronutrient compositions of meal replacements are not crucial for the efficacy of formula diets. Trial registration: German Clinical Trials Register DRKS00005481.

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