Electron Transfer Flavoprotein Subunit Beta is Involved in Behcets Disease
Xiuqin Yang, Peng Chen and Hongwu Du*
School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, PR China
- *Corresponding Author:
- Hongwu Du
112 Lab, School of Chemistry and Biological Engineering
University of Science and Technology Beijing
30 Xueyuan Road,Haidian District
E-mail: [email protected]
Received date: April 25, 2016; Accepted date: June 23, 2016; Published date: June 28, 2016
Citation: Yang X, Chen P, Du H (2016) Electron Transfer Flavoprotein Subunit Beta is Involved in Behcet’s Disease. J Clin Cell Immunol 7:434. doi:10.4172/2155-9899.1000434
Copyright: © 2016 Yang X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This article aim to make a comment on the previous study published entitled “electron transfer flavoprotein subunit beta (ETFB) is a candidate endothelial cell autoantigen in Behcet’s Disease (BD)”. Recently, serum IgG levels of anti-ETFB in BD patients from Shanxi Dayi Hospital were evaluated. The level of IgA against ETFB was also measured in Intestinal Behcet's disease. In addition, correlation of human ETFB, HSP60 and hnRNP-A2/B1 was analyzed. This result verified our previous conclusion. We also discovered that ETFB might be related with mucosal immune, and the pathology of intestinal BD may be related with the infection of intestinal microorganism.