Journal of Clinical and Cellular Immunology
Open Access

Abstract

Electron Transfer Flavoprotein Subunit Beta is Involved in Behcets Disease

Xiuqin Yang, Peng Chen and Hongwu Du

This article aim to make a comment on the previous study published entitled “electron transfer flavoprotein subunit beta (ETFB) is a candidate endothelial cell autoantigen in Behcet’s Disease (BD)”. Recently, serum IgG levels of anti-ETFB in BD patients from Shanxi Dayi Hospital were evaluated. The level of IgA against ETFB was also measured in Intestinal Behcet's disease. In addition, correlation of human ETFB, HSP60 and hnRNP-A2/B1 was analyzed. This result verified our previous conclusion. We also discovered that ETFB might be related with mucosal immune, and the pathology of intestinal BD may be related with the infection of intestinal microorganism.