alexa Emerging Role of Long Non-Coding RNAs in Non-Small Cell Lung Cancer: Progress and Prospects
ISSN: 2167-7700

Chemotherapy: Open Access
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Emerging Role of Long Non-Coding RNAs in Non-Small Cell Lung Cancer: Progress and Prospects

Weijun Wu1, Jieqing Zhao2 and Yongsheng Wang3*

1Department of Clinical Pharmacy, Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing, PR China

2Department of Clinical Pharmacy, Nanjing Xianlin Drum Tower Hospital, Nanjing, PR China

3Department of Respiratory Medicine, Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing, PR China

*Corresponding Author:
Yongsheng Wang
Department of Respiratory Medicine
Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University
Nanjing, 210008, PR China
Tel: 86-025-83106666
Fax: 86-025-68183333
E-mail: [email protected]

Received Date: January 09, 2017; Accepted Date: January 23, 2017; Published Date: January 28, 2017

Citation: Wu W, Zhao J, Wang Y (2017) Emerging Role of Long Non-Coding RNAs in Non-Small Cell Lung Cancer: Progress and Prospects. Chemo Open Access 6:220. doi: 10.4172/2167-7700.1000220

Copyright: © 2017 Wu W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Non-small cell lung cancer (NSCLC), accounts for approximately 80-85% of all lung cancer cases, is the most common cause of cancer-related death worldwide. With the advances of high-throughput sequencing, accumulating evidence suggested that the long non-coding RNA molecules, with transcripts larger than 200 nucleotides, have important roles in multiple biological processes in NSCLC. In this review, we will highlight the emerging roles of long non-coding RNAs (lncRNAs) in NSCLC, discussing both onco-lncRNAs and tum

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