Reach Us +441202068036
Endotracheal Tuberculosis and Aspergillosis Co-Infection Manifested as Acute Respiratory Failure: A Case Report | OMICS International | Abstract
ISSN: 2161-1068

Mycobacterial Diseases
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Endotracheal Tuberculosis and Aspergillosis Co-Infection Manifested as Acute Respiratory Failure: A Case Report

Xerinda S*, Neves N, Santos L and Sarmento A

Infectious Disease Department, University of Porto, Portugal

Corresponding Author:
Sandra Xerinda
Infectious Disease Department-Nephrology Research Development Unit (FCT-725)
Faculty of Medicine, University of Porto
Centro Hospitalar São João, Porto-Portugal
Tel: +351 225512216
Fax: +351 225512216
E-mail: [email protected]

Received Date: May 25, 2014; Accepted Date: July 13, 2014; Published Date: July 20, 2014

Citation: Xerinda S, Neves N, Santos L, Sarmento A (2014) Endotracheal Tuberculosis and Aspergillosis Co-Infection Manifested as Acute Respiratory Failure: A Case Report. J Mycobac Dis 4:160. doi:10.4172/2161-1068.1000160

Copyright: © 2014 Xerinda S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Endotracheal and endobronchial tuberculosis are defined by microbiological and histopathological evidence of tuberculosis involving tracheobronchial tree, with or without parenchymal involvement. Tracheal tuberculosis is a rare and localized form of tuberculosis which can present itself with acute respiratory failure due to upper airway obstruction.

Case presentation: We present a case of a 62 year old female with a diagnosis of pulmonary tuberculosis, who was admitted to the emergency department of our hospital with severe dyspnea, which rapidly progressed to acute respiratory failure requiring tracheal intubation and mechanical ventilation. A four-drug anti-tuberculosis (TB) regimen, consisting of isoniazid, rifampicin, pyrazinamide and ethambutol, was started one month before and identification of a sensitive Mycobacterium tuberculosis strain was made at that time. During medical investigation, tracheobronchial tuberculosis and endotracheal aspergillosis co-infection were diagnosed by bronchoscopy and histological examination.

Conclusion: This uncommon case illustrates a severe clinical presentation of tracheobronchial tuberculosis with concomitant diagnosis of tracheal aspergillosis. It underlines the importance of a prompt diagnosis and treatment of tracheal tuberculosis and co-incidental infections in order to prevent serious complications, such as bronchostenosis and bronchomalacia. The bronchoscopic examination is the key for microbiological and histopathological confirmation of tracheobronchial involvement for both tuberculosis and aspergillosis. Corticosteroid therapy combined with anti-TB regimen remains controversial for endobronchial TB and its impact on patients’ outcome is not well documented.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version