alexa Eosinophilia and Antiphospholipid Antibodies: Double Thrombogenic Hits? A New Case with a Systematic Review | OMICS International | Abstract
ISSN: 2572-9462

Journal of Thrombosis and Circulation: Open Access
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Review Article

Eosinophilia and Antiphospholipid Antibodies: Double Thrombogenic Hits? A New Case with a Systematic Review

Ames PRJ1,*, Merashli M2, Graf M3, Scarpato N3, Arcaro A4 and Gentile F4

1Immune Response and Vascular Disease Unit, Nova University, Lisbon, Portugal

2Muskuloskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK

3Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita Federico II, Napoli, Italy

4Dipartimento di Medicina e Scienze della Salute, Universita’ del Molise, 86100, Campobasso, Italy

Corresponding Author:
Dr. PRJ Ames
Immune Response & Vascular Disease Unit
Nova University, Lisbon, Portugal
E-mail: [email protected]

Received date: January 13, 2016; Accepted date: January 20, 2016; Published date: January 28, 2016

Citation: Ames PRJ, Merashli M, Graf M, Scarpato N, Arcaro A, et al. (2016) Eosinophilia and Antiphospholipid Antibodies: Double Thrombogenic Hits? A New Case with a Systematic Review. J Thrombo Cir 2:103. doi: 10.4172/JTCOA.1000103

Copyright: © 2016 Ames PRJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Peripheral blood eosinophilia (PBE) may be associated with the development of thrombosis and this holds true also for transient PBE though in the latter case the likely hood of thrombosis may not be as high as for long standing PBE. The co-existence of transient PBE with other pro-coagulant factors may precipitate thrombosis in some patients. We report a young gentleman with PBE of unknown cause who developed thrombosis at the peak of his transient PBE and was later found to have antiphospholipid antibodies. We performed a systematic review to evaluate how often the two conditions co-existed, their clinical expression and their management.


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