alexa Epidemiology, Prevention and Control of Hepatitis B vir
E- ISSN: 2320 - 3528
P- ISSN: 2347 - 2286

Research & Reviews: Journal of Microbiology and Biotechnology
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Review Article

Epidemiology, Prevention and Control of Hepatitis B virus Infection in China

Bo Qin1, 2, Guozhong Zhou1, Xuejun Dong1*

1Department of Clinical Laboratory Center, Shaoxing People’s Hospital, Shaoxing Hospital of Zhejiang University, Zhenjiang Province, PR China

2Shaoxing Centre for Disease Control and Prevention, Zhejiang Province, PR China

*Corresponding Author:
Xuejun Dong
Shaoxing People’s hospital
Shaoxing Hospital of Zhejiang University
568 Zhongxing North Road
Shaoxing, Zhejiang
312000, People’s Republic of China
Tel: +86 575 8822 8576
E-mail: [email protected]

Received date: 26/04/2016; Accepted date: 13/06/2016; Published date: 20/06/2016

 

Abstract

Hepatocellular carcinoma (HCC) is one of the major keys to cause cancer-related mortality in the whole world, with the majority of patients related to persistent infection of hepatitis B virus (HBV), especially in Asian and African, while HCV in Europe and America. HBV is the smallest DNA-containing, enveloped mammal virus known so far. High tissue and species specificity, unique genome and replication mechanism make HBV be shrouded in mystery. A high HBV load is the most significant risk element for HCC recurrence. Individuals chronically infected with HBV are 200 times more inclined to develop HCC than uninfected people. Effective antiviral treatment against HBV could alleviate HBV-associated HCC and improve survival. From several aspects including epidemiology, infection, replication of HBV, immune state, anti-HBV therapy and gut microbiota of patients, we made a summary of currently available knowledge about the epidemiology, prevention and control of HBV infection for the organism as a whole.

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