Epigenetics and Codon Usage of the Histone Genes in 12 Drosophila SpeciesYoshinori Matsuo*
Division of Science and Technology, Tokushima University, Tokushima 770-8506, Japan
- *Corresponding Author:
- Matsuo Y
Division of Science and Technology
Tokushima University, 2-1 Minamijosanjima-cho
Tokushima 770-8506, Japan
E-mail: [email protected]
Received date: April 12, 2017; Accepted date: May 02, 2017; Published date: May 15, 2017
Citation: Matsuo Y (2017) Epigenetics and Codon Usage of the Histone Genes in 12 Drosophila Species. J Phylogenetics Evol Biol 5:178. doi: 10.4172/2329-9002.1000178
Copyright: © 2017 Matsuo Y. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Histones are proteins that bind to DNA and form nucleosomes. There are several types of histones that differ in chromosome distribution and timing of their expression. In Drosophila, each canonical type histone is identical or highly similar in amino acid sequence to its corresponding replacement type histone; however, gene structure and codon usage differ between the two types of histones. Identification of the evolutionary changes responsible for the differences between these two histone types will lead to an understanding of the development of epigenetic regulation. Here, recent findings regarding codon usage for canonical and replacement types of histones are outlined for study of the evolution of these histone genes and their epigenetic regulation in Drosophila.