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ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

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Research Article

Epithelioid Osteosarcoma with Pseudo-Glandular Structures: A Case Report and Review of the Literature

Beibei Gao1, Daiqiang Lia1*, Jiaoyun Zheng2, Xiao Fu1, Linrong Tuo1, Xia Wu1 and Junming Luo2*

1Department of Pathology, the Second Affiliated Hospital, Xiangya Medical School, Central South University, 156 Renmin Rd, Changsha, Hunan 410011, P.R. China

2Department of Pathology, Qinghai Provincial People’s Hospital, 2 Gonghe Rd, Xining, Qinghai, P.R. China

*Corresponding Authors:
Daiqiang Li MD
Department of Pathology
the Second Affiliated Hospital
Xiangya Medical School
Central South University, 156 Renmin Rd
Changsha, Hunan 410011, P.R. China
Tel: +86-731-85292139
Fax: +86-731-85292139
E-mail: [email protected]
Junming Luo
Department of Pathology
the Second Affiliated Hospital
Xiangya Medical School
Central South University, 156 Renmin Rd
Changsha, Hunan 410011, P.R. China
Tel: +86-731-85292139
Fax: +86-731-85292139

Received Date: August 01, 2016;; Accepted Date: October 17, 2016; Published Date: October 27, 2016

Citation: Gao B, Lia D, Zheng J, Fu X, Luo J, et al. (2016) Epithelioid Osteosarcoma with Pseudo-Glandular Structures: A Case Report and Review of the Literature. J Cytol Histol 7: 433. doi:10.4172/2157-7099.1000433

Copyright: © 2016 Gao B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Epithelioid osteosarcoma is an uncommon subtype of conventional osteosarcoma that comprised of both typical osteosarcoma component and epithelioid cells. It often occurs in adolescent and children. In here, we report a case of epithelioid osteosarcoma of a 12-year-old Chinese boy. Microscopically, the tumor contains large epithelioid cell with abundant cytoplasm and osteoid forming malignant cells, and partially, the tumor cells arranged in pseudoglandular structures. To our knowledge, it is the first report of epithelioid osteosarcoma with pseudo-glandular structure. The epithelioid cells expressed vimentin and epithelial membrane antigen but did not expressed cytokeratin.

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