Reach Us +44-1993-227344
Escitalopram for Delusion in an Oldest Old Patient with Alzheimer's Disease | OMICS International | Abstract
ISSN: 2168-975X

Brain Disorders & Therapy
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Escitalopram for Delusion in an Oldest Old Patient with Alzheimer's Disease

Sachiko Yokoyama1, Mari Aoki1, Kazunari Azuma1, Koichi Jimbo1, Kimiko Konishi1, Masaki Okada2, Misa Hosoi1 and Koji Hori1,2*
1Department of Psychiatry, Showa University Northern Yokohama Hospital, Kanagawa, Japan
2Department of Psychiatry, Hitachiumegaoka Hospital, Ibaraki, Japan
Corresponding Author : Koji Hori
Department of Psychiatry
Showa University Northern Yokohama Hospital 35-1 Chigasakichuo
Tsuzukiku, Yokohama, Kanagawa 224-8503, Japan
Tel: +81-45-949-7000
Fax: +81-45-949-7927
E-mail: [email protected]
Received Septembet 18, 2013; Accepted October 23, 2013; Published October 25, 2013
Citation: Yokoyama S,Aoki M, Azuma K, Jimbo K, Konishi K, et al. (2013) Escitalopram for Delusion in an Oldest Old Patient with Alzheimer’s Disease. Brain Disord Ther 2:108. doi:10.4172/2168-975X.1000108
Copyright: © 2013 Yokoyama S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: To present a case of Alzheimer’s disease (AD) associated with delusions that were satisfactorily treated with escitalopram. Background: In Japan, there are currently no licensed medicines for the management of the behavioral and psychological symptoms of dementia (BPSD) in AD patients. Patient and Results: We present the case of an 88-year-old woman with AD who developed delusions that were successfully treated with escitalopram. We previously reported that anxiety in elderly AD patients was associated with delusions and hallucinations and was caused by disturbance of the serotonergic system. Therefore, we considered that enhancement of the serotonergic system may be useful for ameliorating delusion in the present AD patient. Escitalopram inhibits the reuptake of serotonin and experts allosteric potentiating actions on serotonin reuptake inhibitors, moreover, it has evidence of efficacy for treating affective symptoms in the old patients. Therefore, this agent may be useful for ameliorating serotonin deficiency and delusion in the oldest old AD patients. Conclusions: Escitalopram may be useful for the management of psychotic symptoms in relatively older patients with AD.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7