Etiologies and Initial Evaluation of Neonatal Jaundice
Sydur Rahman and Matthew D. Alvin*
Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
- Corresponding Author:
- Matthew D. Alvin
Johns Hopkins Hospital
Johns Hopkins University School of Medicine
Baltimore, Maryland, USA
Tel: +1 410 516 8171, +1(347)2516781
E-mail: [email protected]
Received April 17, 2016; Accepted May 07, 2016; Published May 11, 2016
Citation: Rahman S, Alvin MD (2016) Etiologies and Initial Evaluation of Neonatal Jaundice. J Neonatal Biol 5:220. doi: 10.4172/2167-0897.1000220
Copyright: © 2016 Rahman S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Neonatal jaundice is seen in up to 60% of full-term infants and 80% of preterm infants during the first week of life. While it is often considered as a single clinical entity, neonatal jaundice is a physical finding associated with many possible etiologies. Jaundice is observed when the pigment bilirubin accumulates in the skin, sclera and other tissues. The importance of correctly identifying the etiology of neonatal jaundice lies in the necessity of intervening early to avoid the devastating sequelae of prolonged hyperbilirubinemia, namely bilirubin-induced neurological dysfunction (BIND), formerly kernicteruskernicterus. This manuscript provides a framework for thinking about the etiologies of neonatal jaundice with respect to type of hyperbilirubinemia (direct vs. indirect) and age of the newborn.