Etiopathogenesis of Alopecia AreataYasmeen J Bhat*, Peerzada Sajad and Iffat Hassan
Department of Dermatology, STD & Leprosy, Government Medical College, University of Kashmir, Srinagar, J&K- India
- *Corresponding Author:
- Yasmeen J Bhat
Department of Dermatology, STD & Leprosy
Government Medical College, Srinagar (J&K), India
Email: [email protected]
Received date: March 22, 2014; Accepted date: April 22, 2014; Published date: April 28, 2014
Citation: Bhat YJ, Sajad P, Hassan I (2014) Etiopathogenesis of Alopecia Areata. Hair Ther Transplant 4:123. doi: 10.4172/2167-0951.1000123
Copyright: © 2014 Bhat YJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Alopecia areata (AA) is a recurrent, non-scarring type of hair loss affecting the hair follicles and sometimes the nails. Current evidence indicates that hair follicle inflammation in alopecia areata is caused by a T-cell mediated autoimmune mechanism occurring in genetically predisposed individuals. Environmental factors like infections, diet, vaccination and stress may be responsible for triggering the disease. The association between alopecia areata and other autoimmune diseases suggests that alopecia areata is itself an autoimmune disease. Recently many cytokines have been implicated in the pathogenesis of AA and these are focused upon in this article.