alexa EV71, A Virus with Complicated Pathogenesis in the CNS
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Review Article

EV71, A Virus with Complicated Pathogenesis in the CNS

Min Feng and Qihan Li*
Institute of Medical Biology, Chinese Academy of Medicine Sciences & Peking Union Medical College, Kunming, 650118, China
Corresponding Author : Qihan Li
Institute of Medical Biology Chinese Academy of Medicine Sciences and
Peking Union Medical College, China
Tel: 86-871-68335905
Fax: 86-871-68334483
E-mail: [email protected]
Received June 02, 2014; Accepted July 15, 2014; Published July 20, 2014
Citation: Feng M, Li Q (2014) EV71, A Virus with Complicated Pathogenesis in the CNS. J Infect Dis Ther 2:153. doi:10.4172/2332-0877.1000153
Copyright: © 2014 Feng M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Fatal cases of hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) infection are characterized by inflammatory damage to the central nervous system (CNS) with slight degeneration of nerve cells. Here, we review several studies that identify potential host factors and possible mechanisms of neuropathogenesis of EV71 infection.


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