alexa Evaluating Social Support-Like Phenomena in an Animal M
ISSN: 2167-1044

Journal of Depression and Anxiety
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Evaluating Social Support-Like Phenomena in an Animal Model of Posttraumatic Stress Disorder (PTSD)

Christoph K Thoeringer1,2 and Carsten T Wotjak2
1II Med. Klinik, Klinikum rechts der Isar, Technical University of Munich, Germany
2Max Planck Institute of Psychiatry, Munich, Germany
*Corresponding Author : Christoph K Thoeringer
II Med. Klinik, Klinikum rechts der Isar
Technical University of Munich, Ismaninger Strasse 22
81675 Munich, Germany
Tel: +49-89-4140-2251
Received October 24, 2013; Accepted December 13, 2013; Published December 16, 2013
Citation: Thoeringer CK, Wotjak CT (2013) Evaluating Social Support-Like Phenomena in an Animal Model of Posttraumatic Stress Disorder (PTSD) J Depress Anxiety 3:143. doi:10.4172/2167-1044.1000143
Copyright: © 2013 Thoeringer CK, er al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Social interactions contribute significantly to emotional regulation and, hence, foster resilience for psychopathological states and diseases. In particular, social support is supposed to buffer the development and distress in Posttraumatic Stress Disorder (PTSD). In the present study, we investigated the effect of different adult social housing conditions, i.e., socially isolated vs. paired housing in dyads, and the presence of social support regarding development and maintenance of PTSD-like symptoms in a mouse model of PTSD. In a first analysis, we could not detect effects of single versus dyad housing of male mice on unconditioned anxiety, acoustic startle reactivity or sensitized and conditioned long-term fear. However, mice housed in dyads displayed enhanced extinction of contextual fear 1 month after trauma. In a second analysis, we did not find evidence for social support-like phenomena among dyad housed animals, if traumatized mice were cohabited with a non-traumatized animal.In summary, we could not detect social support-like phenomena among dyad housed male mice on the development and expression of PTSD-like symptoms in an animal model, but impaired extinction of remote contextual fear in singlehoused mice.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version