Evaluation and Rearrangement of Novel Supramolecular 7-(2,3-dihydro- 1,3-benzothiazol-2-yl)quinolin-8-ol Complexes and their Biological Effect*Corresponding Author: El-Sonbati AZ, Chemistry Department, Faculty of Science, Damietta University, Damietta 34517, Egypt, Tel: +201060081581, Fax: +20 572403868, Email: [email protected]
Received Date: Jul 28, 2014 / Accepted Date: Aug 12, 2014 / Published Date: Aug 19, 2014
Citation: El-Sonbati AZ, Diab MA, El-Bindary AA, Nozha SG, Nassar MI (2014) Evaluation and Rearrangement of Novel Supramolecular 7-(2,3-Dihydro-1,3-benzothiazol-2-yl)quinolin-8-ol Complexes and their Biological Effect. J Microbial Biochem Technol S4:001.DOI: 10.4172/1948-5948.S4-001
Copyright: © 2014 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Novel tridentate Schiff base ligand derived from the 2-aminobenzenthiol and 8-hydroxy-7-quinolinecarboxaldehyde (oxine) and its metal complexes have been prepared. The reaction of a solution of 7-(2,3-dihydro-1,3-benzothiazol- 2-yl)quinolin-8-ol (H2L) with di-and tetravalent transition metals have been studied chemically and biologically. The optimized bond lengths, bond angles and calculated the quantum chemical parameters for the ligand (H2L) [the cyclic form (A) and the Schiff base form (B)] were investigated. The complexes have been characterized by elemental analyses, IR spectra, thermal analyses and 1H-NMR spectroscopy. The spectral studies of the isolated complexes showed that the rearrangement of the benzothiazoline to the Schiff base had occurred. The data suggest that the Co(II) and Ni(II) complexes are binuclear and octahedral dimmers, while the rest are monomeric with square planar/ tetrahedral geometries. The ESR spectrum of the Cu(II) complex show axial type symmetry with gll > gÃ¢Â”Â´>2.0023, indicating dx2-y2 ground state with significant covalent bond character. Five doses were topically applied against the newly emerged adults of the red palm weevil Rhynchophorus ferrugineus. Percent of adult mortality was 98.2%, which occurred after adult treatment with the highest dose (2.2 mg/ml) of Ni(II) complex. The lowest mortality was 5.6% which obtained due to effect of oxine after adult was treated with dose of 0.25 mg/ml. Five doses were topically applied against the newly emerged adults of the stored product weevil, Sitophilus granaria. While the lower mortality, 5% caused due to effect of least dose, 0.15 mg/ml of the compound oxine.