alexa Evaluation of Antimicrobial Activity of Synthesized Silver Nanoparticles using Phyllanthus amarus and Tinospora cordifolia Medicinal Plants
ISSN: 2157-7439

Journal of Nanomedicine & Nanotechnology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Evaluation of Antimicrobial Activity of Synthesized Silver Nanoparticles using Phyllanthus amarus and Tinospora cordifolia Medicinal Plants

Khushboo Singh, Manju Panghal, Sangeeta Kadyan and Jaya Parkash Yadav*

Department of Genetics, M.D. University, Rohtak-124001, Haryana, India

*Corresponding Author:
Jaya Parkash Yadav
Department of Genetics
M.D. University
Rohtak-124001, Haryana, India
Tel: 91-9416474640
E-mail: [email protected]

Received Date: November 03, 2014; Accepted Date: December 03, 2014; Published Date: December 13, 2014

Citation: Singh K, Panghal M, Kadyan S, Yadav JP (2014) Evaluation of Antimicrobial Activity of Synthesized Silver Nanoparticles using Phyllanthus amarus and Tinospora cordifolia Medicinal Plants. J Nanomed Nanotechnol 5:250. doi:10.4172/2157-7439.1000250

Copyright: © 2014 Singh K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The main aim of this study is to evaluate the comparison of antimicrobial efficacy of silver nanoparticles synthesized from aqueous plant extracts of Phyllanthus amarus and Tinospora cordifolia. The synthesized silver nanoparticles were characterzed by UV-VIS spectroscopy, Fourier Transform Infra-Red spectroscopy, Transmission Electron Microscopy, Dynamic Light Scattering and zeta potential. The antimicrobial activity of synthesized silver nanoparticles was compared with their respective plant extracts by agar well diffussion method and minimum inhibitory concentration was also calculated. The zone of inhibition varied in range of 12 ± 1 to17 ± 0.58 mm with 100 μg/ml silver nanoparticles concentration, while acetonic, methanolic and aqueous extracts of respective plants does not showed any activity even at 1 mg/ml i.e. 10 times more than that of silver nanoparticles. MIC of silver nanoparticles was found to be in a range of 6.25-25 μg/ml against all tested microbes. The antimicrobial activity of synthesized silver nanoparticles was higher than that of the standard drug i.e. streptomycin (for bacteria) and ketoconazole (for fungus). The synthesized nanoparticles of P. amarus and T. cordifolia have shown good antimicrobial efficacy as compared to plant extracts and may prove to be better antimicrobial agent against wide range of microbes.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version