alexa Evaluation of Biocompatibility of Chitosan Films from the Mycelium of Aspergillus niger in Connective Tissue of Rattus norvegicus | OMICS International | Abstract
ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Evaluation of Biocompatibility of Chitosan Films from the Mycelium of Aspergillus niger in Connective Tissue of Rattus norvegicus

Danny Javier Balanta Silva1, Fabio Zuluaga1* and Carlos H2

1Departamento de Química, Universidad del Valle. Cali, Colombia

2Escuela de Odontología, Universidad del Valle. Cali, Colombia

Corresponding Author:
Fabio Zuluaga
Departamento de Química
Universidad del Valle. Cali
Colombia
E-mail: [email protected]

Received Date: May 29, 2015 Accepted Date: July 20, 2015 Published Date: July 27, 2015

Citation: Silva DJB, Zuluaga F, Valencia CH (2015) Evaluation of Biocompatibility of Chitosan Films from the Mycelium of Aspergillus niger in Connective Tissue of Rattus norvegicus. J Mol Genet Med 9:174. doi:10.4172/1747-0862.1000174

Copyright: © 2015 Silva DJB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

Chitosan was extracted from Aspergillus niger mycelium and characterized by several techniques (FTIR, 1HNMR y 13C-CP-MAS-NMR, TGA, DSC and XRD) with a reaction yield of 5.02%, and its average viscosity molecular weight was 1.52 x 105 g/mol. Deacetylation degree was determined by elemental analysis and 1H-NMR, being around 75%. Chitosan films were obtained by film casting, using glycerol and oleic acid as plasticizers, the chitosan films were characterized by SEM and XRD. Degradability in vitro tests under physiological conditions, mechanical tests, and biocompatibility tests on Rattus norvegicus were run, followed by histological studies of connective tissue samples from the site where the films were implanted finding complete absorption of the material and no damage to nearby tissues.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7