Journal of Clinical and Experimental Ophthalmology
Open Access

Abstract

Evaluation of Central Corneal Thickness and Corneal Endothelial Cell Parameters in Pseudoexfoliative Glaucoma

Gazala Ahmad, Shahzada Sajid Bashir Banday, Junaid S Wani and Shahzada Shahid Bashir Banday

Background: The characteristics of corneal endothelium in patients with pseudoexfoliation (PEX) have been unclear. This study aimed to evaluate the corneal endothelial cell density and morphology in eyes diagnosed with this syndrome at our institution.
Objective: To measure central corneal thickness and corneal endothelial cell parameters in pseudoexfoliative glaucoma.
Methods: Ocular examination in all patients was performed with slit lamp examination, gonioscopy with Goldmann two mirror indirect gonioscope and dilated fundus examination using +90 D lens.
Results: No significant differences were found in the demographic parameters (age and sex) among the patients of two groups. Mean CCT value was significantly lower in PXG group 556.4+28.95 than in control group (572.5+19.91). Mean percentage of Hexagonal cells and the coefficient of variation in PXG group (2239.5+254.33), (50.9+2.47) and (37.6+2.09) were also found to have statistically significant difference compared to control group (2554.2+164.65), (56.1+4.06) and (34.4+2.15).
Conclusion: The study confirms the existence of significant difference in various corneal morphometric parameters in PXG patients.