alexa Evaluation of Metastatic Cholangiocarcinoma in a Spitz Dog
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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Case Report

Evaluation of Metastatic Cholangiocarcinoma in a Spitz Dog

Farhang Sasani1, Fariba Khaki1, Shahram Jamshidi2, Javad Javanbakht1* and Mehdi Aghamohammad Hassan2

1Department of Pathology, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

2Department of Clinical Sciences, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

*Corresponding Author:
Dr. Javad Javanbakht
Department of Pathology
Faculty of Veterinary Medicine
Tehran University, Tehran, Iran
Tel: +989372512581
E-mail: [email protected]

Received date: February 01, 2013; Accepted date: February 28, 2013; Published date: March 03, 2013

Citation: Javanbakht J, Sasani F, Khaki F, Jamshidi S, Hassan MA, et al. (2013) Evaluation of Metastatic Cholangiocarcinoma in a Spitz Dog. J Cancer Sci Ther 5:113-114. doi: 10.4172/1948-5956.1000194

Copyright: © 2013 Javanbakht J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



A 12-year-old spitz breed dog, with progressive neurologic symptoms including seizures, ataxia, mental
depression, walking aimlessly and head pressing was referred to Small Animal Hospital of Veterinary Medicine,
the University of Tehran. The dog was received Diazepam prior to examination and diagnosis, whereas it died
at first day eventually. In physical examination, there was a firm mass with irregular nodular surface, about 8
cm in diameter under the skin of mammary glands region. At necropsy, considerable abdominal ascites, several
masses with different sizes throughout liver lobes and on intestinal serosa were observed. According to histological
adjectives of biliary epithelium due to firm texture of the tumour masses and numerous mitotic figures the tumour
was confirmed as cholangiocarcinoma, and immuniohistochemical results for cytokeratin marker demonstrated
such diagnosis.

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