Evaluation of Multiple Sleep-Related Parameters in Patients with Obstructive Sleep Apnea in Different Age Ranges
|Gilbert Seda1*, Carolyn H Welsh2, Massoud Daheshia1, John Perri1 and David Bradshaw1|
|1Department of Pulmonary and Critical Care Medicine, Naval Medical Center San Diego, San Diego, CA 92134, USA|
|2Denver Veterans Affairs Medical Center, Denver, Colorado, USA|
|Corresponding Author :||Gilbert Seda
Department of Pulmonary and Critical Care Medicine
Naval Medical Center San Diego, San Diego, CA 92134, USA
E-mail: [email protected]
|Received August 25, 2013; Accepted September 13, 2013; Published September 17 2013|
|Citation: Seda G, Welsh CH, Daheshia M, Perri J, Bradshaw D (2013) Evaluation of Multiple Sleep-Related Parameters in Patients with Obstructive Sleep Apnea in Different Age Ranges. J Sleep Disord Ther 2:140. doi:10.4172/2167-0277.1000140|
|Copyright: © 2013 Seda G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Purpose: No age-based comparative studies have investigated clinical and polysomnographic manifestations of adults with Obstructive Sleep Apnea (OSA).
Methods: Retrospective record review of 570 patients with OSA at Naval Medical Center San Diego. Patients were divided into one of four age cohorts: (1) ages 18-29 (n=209); (2) ages 30-39 (n=106); (3) ages 40-49 (n=102); and (4) ages > 50 (n=153). Group comparisons of demographics, Epworth Sleepiness Scale (ESS), Patient Sleep Questionnaire (PSQ), and polysomnography were analyzed.
Results: Patients, ages 18-29 reported more witnessed apneas, Excessive Daytime Sleepiness (EDS), and had higher respiratory related arousal indexes (p=0.018) compared to patients over 30 years old. Patients 50 years and older reported more nocturia (p=0.001), less snoring, and had higher Rapid Eye Movement (REM)-related apneas (p=0.008), and more severe oximetry desaturations than patients less than 50 years old (p=0.001 - 0.004). Age groups were similar with respect to Body Mass Index (BMI), self-reported sleep-related driving impairment, Apnea Hypopnea Index (AHI), non-REM (NREM) AHI, and total obstructive and central apneas.
Conclusions: Snoring, EDS, nocturia, arousal index, and lowest oxygen saturation most significantly differentiated OSA across different age groups of patients with OSA.