alexa Evaluation of Physiochemical, Phytochemical, Antioxidant and Antimicrobial Screening Parameters of Amaranthus spinosus Leaves
ISSN: 2329-6836

Natural Products Chemistry & Research
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Research Article

Evaluation of Physiochemical, Phytochemical, Antioxidant and Antimicrobial Screening Parameters of Amaranthus spinosus Leaves

Teklit Gebregiorgis Amabye*
Department of Chemistry, College of Natural and Computational Science, Mekelle University, Mekelle, Ethiopia
Corresponding Author : Teklit Gebregiorgis Amabye
Department of Chemistry
College of Natural and Computational Science
Mekelle University, Mekelle, Tigray, Ethiopia
Tel: +251945523645
E-mail: [email protected]
Received December 01, 2015; Accepted December 17, 2015; Published December 19, 2015
Citation: Amabye TG (2015) Evaluation of Physiochemical, Phytochemical, Antioxidant and Antimicrobial Screening Parameters of Amaranthus spinosus Leaves. Nat Prod Chem Res 4:199. doi:10.4172/2329-6836.1000199
Copyright: © 2015 Amabye TG. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

This study was carried out in methanol extracts of the dried leaves of Amaranthus spinosus were collected and used for phytochemicals, physiochemical and antibacterial analysis. By detecting the MIC (Minimum Inhibitory Concentration) and zone inhibition, the antibacterial activity was determined against different bacterial and fungal strains. The extract yields from the leaves was 6.97 methanol w/w. Phytochemical investigation of this plant determines that tannins 6.07%, Saponins 53%, alkaloids 13.14%, proteins 16.76% and glycosides 63.2% were rich in leaves. The extracts also contained appreciable levels of total phenolic contents 2.81 in GAE, g/100 g, total flavonoid contents 18.4 QE, g/100 and the free radical scavenging activity, showing IC50 (83.45 μg/mL) along with reducing power was calculated. The minimum inhibition concentration of extracts shows that 178 μg/mL. The physiochemical result obtained can be used for the identification of powdered drugs. The whole plant is used as a laxative. Traditionally it has been used as diuretic, antidiabetic, antipyretic, anti-snake venom, antileprotic, anti-gonorrheal, anti-inflammatory, and anthelmintic and immunomodulatory. The root paste of the plant is used to cure skin disease. A red pigment obtained from the plant is used for coloring foods and medicines. The results of this study suggest the possibility of using the methanol extract in treating the diseases caused by the tested organisms.

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