alexa
Reach Us +44-1647-403003
Evaluation of Prognostic Significance of Immunological Cells (Tissue Eosinophil and Mast Cell) Infiltration in Oral Squamous Cell Carcinoma | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Evaluation of Prognostic Significance of Immunological Cells (Tissue Eosinophil and Mast Cell) Infiltration in Oral Squamous Cell Carcinoma

Priyanka Debta1*, Fakir Mohan Debta2, Minal Chaudhary3 and Vijay Wadhwan4

1Department of Oral Pathology and Microbiology, Chhattisgarh Dental College and Research institute, India

2Department of Oral Medicine & Radiology, C.D.C.R.I. Sundra, Rajnandgaon, Chhattisgarh, India

3Department of Oral Pathology and Microbiology, S.P.D.C., Sawangi, Wardha, Maharashtra, India

4Department of Oral Pathology and Microbiology, I.T.S. Dental College, Murad Nagar, Ghaziabad, India

*Corresponding Author:
Dr. Priyanka Debta, MDS
Senior Lecturer, Oral Pathology and Microbiology
Staff Quarter No. 8/16, College campus Chhattisgarh
Dental College and Research institute, PB No.25
Sundra, Rajnandgaon, (C.G.) 491441, India
Tel: 09685714325
E-mail: [email protected]

Received Date: August 08, 2011; Accepted Date: September 17, 2011; Published Date: September 19, 2011

Citation: Debta P, Debta FM, Chaudhary M, Wadhwan V (2011) Evaluation of Prognostic Significance of Immunological Cells (Tissue Eosinophil and Mast Cell) Infiltration in Oral Squamous Cell Carcinoma. J Cancer Sci Ther 3: 201-204. doi: 10.4172/1948-5956.1000089

Copyright: © 2011 Debta P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: In oral carcinoma much effort has been made to predict the prognosis of patients but a sound understanding of underlying cell biology is likely to need progress. Recently, attention has been directed towards tumour associated tissue eosinophils and mast cells and their role in the biologic behavior of tumours. Aim: The retrospective study was used to evaluate the influence of tumour associated tissue eosinophils and mast cells on prognosis of oral squamous cell carcinoma (OSCC). Material and methods: The follow-up, of histopathologically diagnosed thirty cases of OSCC, was carried out for minimum period of 3 years. Special stains are wonderful they allow us to see which we can not see clear with routine H&E stain.Tissue sections were stained with special stains, Carbol Chromotrope for tissue eosinophil and Toluidine blue for tissue mast cell staining. Result: The results of the present study shows that increase infiltration of tissue eosinophils and mast cells in OSCC, associated with favourable prognosis. Conclusion: We concludes that infiltration of tissue eosinophils and mast cells are indicators of favourable prognosis in OSCC. Thus quantitative assessment of eosinophils and mast cells are the most important aspects of the microscopic evaluation of OSCC.

Keywords

Share This Page
Top