alexa Evaluation of Wound Healing Ability with Human Embryonic Stem Cells in Patients with Non-Healing Wounds: A Case Series | OMICS International | Abstract
ISSN: 2376-0427

Dermatology and Dermatologic Diseases
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Previously: Journal of Pigmentary Disorders

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Case Report

Evaluation of Wound Healing Ability with Human Embryonic Stem Cells in Patients with Non-Healing Wounds: A Case Series

Geeta Shroff1*, Rakesh Gupta2 and Lalit Kumar Makhija3
1MBBS, Director, Nutech Mediworld, New Delhi, India
2Senior Consultant, Department of Internal Medicine, Apollo Hospital, New Delhi, India
3Head of Department, Department of Burns and Plastic Surgery, Ram Manohar Lohia (RML) Hospital, New Delhi, India
Corresponding Author : Dr. Geeta Shroff
Nutech Mediworld, H-8, Green Park Extension
New Delhi, India-110016
Tel: +91 11 26565548
Fax: +91 11 46057841
E-mail: [email protected]
Received April 20, 2015; Accepted May 20, 2015; Published May 31, 2015
Citation: Shroff G, Gupta R, Makhija LK (2015) Evaluation of Wound Healing Ability with Human Embryonic Stem Cells in Patients with Non-Healing Wounds: A Case Series. Pigmentary Disorders 2:191. doi:10.4172/2376-0427.1000191
Copyright: © 2015 Shroff G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Wound healing occurs by regeneration or repair in which the damaged tissue at the wound site is replaced with fibroblastic mediated scar tissue. However, inadequate cell repair due to poor vascularity at the wound site results in non-healing wounds. This study evaluated the effect of human embryonic stem cell (hESC) therapy in six patients with non-healing wounds. The wound was cleaned and washed with normal saline and cotton gauze. The ready to use form of hESCs was sprayed on the wound and final dressing was done with antibiotics, vaseline gauze and cotton pads. The wounds of all the patients healed after receiving hESC therapy. Reduction in the size of wounds and granulation was observed among all the patients. hESC therapy showed improved and faster wound healing in non-healing wounds of different etiologies.

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