alexa Evolutionary Distance and Conserved Domain Analysis of Divergent Phylogenetic Lineages from Genus Naja
ISSN: 2153-0602

Journal of Data Mining in Genomics & Proteomics
Open Access

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Research Article

Evolutionary Distance and Conserved Domain Analysis of Divergent Phylogenetic Lineages from Genus Naja

Sherkhane AS and Gomase VS*

The Global Open University, India

*Corresponding Author:
Gomase VS
The Global Open University
Nagaland,India
Tel: 91-998-777-0696
E-mail: [email protected]

Received date: May 21, 2014;Accepted date: August 20, 2014; Published date: August 25, 2014

Citation: Sherkhane AS, Gomase VS (2014) Evolutionary Distance and Conserved Domain Analysis of Divergent Phylogenetic Lineages from Genus Naja. J Data Mining Genomics Proteomics 5:156. doi:10.4172/2153-0602.1000156

Copyright: 2014 Sherkhane AS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

 Naja Naja is one of the poisonous snakes in the genus Naja of Elapids family; commonly called Indian cobras and are mostly found in Asia and Africa. They are highly venomous species having a cocktail of chemicals that have different effects may be speed the heart rate, blood pressure and interfere with the normal function of the nervous system and potently block α7 homo-oligomeric neuronal AChRs causing paralysis. The aim of the present study is to identify the origin of neurotoxin, prediction of structure and function of neurotoxin by multiple sequences analysis and observing the conserved pattern of amino acid residues and to construct the phylogenetic tree for organizing evolutionary history of N. Naja of genus Naja from Elapidae family.

 

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