Exercise and Anti-Osteoporotic Medication Combined Treatment for OsteoporosisToumi H1,2*, Best TM3, Cesaro A2 and Lespessailles E1,2
- Corresponding Author:
- Toumi H
Service de Rhumatologie
Centre hospitalier régional d’Orléans
1 rue Porte Madeleine 45032
Tel: 0033 0683483268
E-mail: [email protected]
Received date: February 22, 2016; Accepted date: March 10, 2016; Published date: March 17, 2016
Citation: Toumi H, Best TM, Cesaro A, Lespessailles E (2016) Exercise and Anti-Osteoporotic Medication Combined Treatment for Osteoporosis. J Yoga Phys Ther 6:232. doi:10.4172/2157-7595.1000232
Copyright: © 2016 Toumi H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Antiosteoporotic medications are often used to reduce fracture risk and treat osteoporosis. Similarly, regular physical activity also plays an important role in both maintaining and improving bone density. Recently, it has been shown that exercise combined with osteoporosis medications may produce greater benefits on bone associated with osteoporosis than either intervention alone. This commentary evaluates the current literature mostly produced in our laboratory from animal models to determine the optimal combination of physical exercise and medications on osteoporosis induced by ovariectomy and exogenous glucocorticoids. The data suggest that both approaches enhance bone healing, however the combined effects of these two therapies do not appear to produce any remarkable synergetic or additive effects. Clinical studies are needed to fully understand the effects of exercise and selective medications on bone remodelling in order to optimise treatment of fragility fractures in patients with underlying osteoporosis.