Expression of Surface Molecules on Multiple Myeloma Cells and their Potential Role in Pathogenesis, Prognosis, and Treatment
Katarzyna Kotwica*, Maria B.Cioch, Anna Dmoszynska
Department of Hemato-oncology and Bone Marrow Transplantation, Lublin, Poland
- *Corresponding Author:
- Dr. K. Kotwica
Department of Hematooncology and Bone Marrow Transplantation
Medical University of Lublin
Staszica 11, PL–20-080 Lublin (Poland)
E-mail: [email protected]
Received Date: November 19, 2010; Accepted Date: January 25, 2011; Published Date: January 28, 2011
Citation: Kotwica K, Cioch MB, Dmoszynska A (2011) Expression of Surface Molecules on Multiple Myeloma Cells and their Potential Role in Pathogenesis, Prognosis, and Treatment. J Mol Biomark Diagn 2:103. doi:10.4172/2155-9929.1000103
Copyright: © 2011 Kotwica K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Multiple myeloma cells express a number of surface molecules capable of activating downstream anti-apoptotic signaling pathways which could favor their growth and survival. Such cell surface molecules have been considered to be prognostic factors for multiple myeloma (MM), as detailed in the following review, and, we speculate, may become possible therapeutic targets in the future.