alexa Expression of Toll-like Receptor 9 in Cervical Intraepi
ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Expression of Toll-like Receptor 9 in Cervical Intraepithelial Neoplasia from Mexican Women

Mario Adán Moreno-Eutimio1, Gustavo Acosta-Altamirano2 and Víctor Manuel Vargas-Hernández2*

1Immunobiology Laboratory, Juarez Hospital of Mexico, Mexico City, Mexico

2Research Directorate, Juarez Hospital of Mexico, Mexico City, Mexico

*Corresponding Author:
Víctor Manuel Vargas-Hernández
Dirección de Investigación
Hospital Juárez de México. Av. Instituto Politécnico Nacional 5160
Colonia: Magdalena de las Salinas. CP: 07760
Delegación: Gustavo A. Madero. México, D. F
Tel: (55) 5747 7503
E-mail: [email protected]

Received date: July 11, 2013; Accepted date: September 05, 2013; Published date: September 09, 2013

Citation: Moreno-Eutimio MA, Acosta-Altamirano G, Vargas-Hernández VM (2013) Expression of Toll-like Receptor 9 in Cervical Intraepithelial Neoplasia from Mexican Women. J Cytol Histol 4:181. doi:10.4172/2157-7099.1000181

Copyright: © 2013 Moreno-Eutimio MA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Introduction: Cervical cancer is a major health problem, is the second leading cause of cancer death in women worldwide and the first in developing countries. Toll-like receptors play an important role in the immune system through the recognition of pathogen-associated molecular patterns and damage associated with endogenous molecules, so that the role of Toll-like receptors is being explored in cancer.

Objective: To evaluate the expression of Toll-like receptor 9 (TLR9) in cervical intraepithelial neoplasia grade I, II and III tissues using immunohistochemical staining.

Material and Methods: Retrospective, observational and descriptive study, the expression of TLR9 incervical intraepithelial neoplasia grade I (n=124), II (n=68) and III (n=29) tissues were evaluated using immunohistochemical staining. All samples used in this study were from Mexican women.

Results: We found the expression levels of TLR9 was higher in CIN I (p<0.001) and CIN-II (p<0.001) than in CIN-III.

Conclusion: The low expression of TLR9 may play important roles in the development and progression of cervical intraepithelial neoplasia in Mexican women.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords