Fabrication of Liquid Molds using Drop-on-demand Printing Technology for Bio-Pdms Mirofluidic Devices
Lijun Yang*, Baochun Lu, Li Zhu, and Xiaoyang Zhu
Microsystem Lab, School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu, China
- *Corresponding Author:
- Lijun Yang
Microsystem Lab, School of Mechanical
Engineering, Nanjing University of Science and
Technology, Nanjing, Jiangsu, China
E-mail: [email protected]
Received Date: October 05, 2015; Accepted Date: October 12, 2015; Published Date: October 21, 2015
Citation: Yang L, Lu B, Zhu L, Zhu X (2015) Fabrication of Liquid Molds using Drop-on-demand Printing Technology for Bio-Pdms Mirofluidic Devices. J Biosens Bioelectron 6:185. doi:10.4172/2155-6210.1000185
Copyright: © 2015 Yang L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A simple and easy method is demonstrated for the fabrication of liquid molds which was used for the fabricaion of bio-polydimethylsiloxan (Bio-PDMS) mirofluidic devices based on a novel drop-on-demand (DOD) printing technology. The liquid molds were DOD printed well on the hydrophilic glass substrate which was treated with a TiO2 nanoparticles (TiO2NPs) solution at the overlap of 30%. Then the PDMS concave molds were fabricated well by being replicated from the liquid molds and were bonded with another PDMS substrate to form a Bio-PMDS mirofluidic device. The micro-channel which the width and the height were about 100 μm and 8 μm was fabricated and the surface roughness of the micro-channel with the 100×320 μm2 area was about 179 nm measured by a white light interferometer. The experimental results showed that the width of micro-channel in the Bio-PDMS microfluidic device was small and the surface of the micro-channel was smooth.