alexa Fabrication of Liquid Molds using Drop-on-demand Printing Technology for Bio-Pdms Mirofluidic Devices
ISSN: 2155-6210

Journal of Biosensors & Bioelectronics
Open Access

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Research Article

Fabrication of Liquid Molds using Drop-on-demand Printing Technology for Bio-Pdms Mirofluidic Devices

Lijun Yang*, Baochun Lu, Li Zhu, and Xiaoyang Zhu

Microsystem Lab, School of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu, China

*Corresponding Author:
Lijun Yang
Microsystem Lab, School of Mechanical
Engineering, Nanjing University of Science and
Technology, Nanjing, Jiangsu, China
Tel: +86-025-84315031
E-mail: [email protected]

Received Date: October 05, 2015; Accepted Date: October 12, 2015; Published Date: October 21, 2015

Citation: Yang L, Lu B, Zhu L, Zhu X (2015) Fabrication of Liquid Molds using Drop-on-demand Printing Technology for Bio-Pdms Mirofluidic Devices. J Biosens Bioelectron 6:185. doi:10.4172/2155-6210.1000185

Copyright: © 2015 Yang L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

A simple and easy method is demonstrated for the fabrication of liquid molds which was used for the fabricaion of bio-polydimethylsiloxan (Bio-PDMS) mirofluidic devices based on a novel drop-on-demand (DOD) printing technology. The liquid molds were DOD printed well on the hydrophilic glass substrate which was treated with a TiO2 nanoparticles (TiO2NPs) solution at the overlap of 30%. Then the PDMS concave molds were fabricated well by being replicated from the liquid molds and were bonded with another PDMS substrate to form a Bio-PMDS mirofluidic device. The micro-channel which the width and the height were about 100 μm and 8 μm was fabricated and the surface roughness of the micro-channel with the 100×320 μm2 area was about 179 nm measured by a white light interferometer. The experimental results showed that the width of micro-channel in the Bio-PDMS microfluidic device was small and the surface of the micro-channel was smooth.

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