Factor XI Deficiency: First Case Described in Algeria
Abdessamed Arabi*, Mohamed Chekkal, Leila Charef, Samira Bouchama, Sihem Mehded, Mohamed Brahimi, Nabil Yafour and Mohamed-Amine Bekadja
Haematology and Cell Therapy Unit, Etablissement Hospitalier et Universitaire 1er Novembre 1954 Oran, Algeria
- *Corresponding Author:
- Abdessamed Arabi
Haematology and Cell Therapy Unit
Etablissement Hospitalier et
Universitaire 1er Novembre 1954 Oran, Algeria
E-mail: [email protected]
Received date: July 15, 2015 Accepted date: August 18, 2015 Published date: August 22, 2015
Citation:Arabi A, Chekkal M, Charef L, Bouchama S, Mehded S, et al. (2015) Factor XI Deficiency: First Case Described in Algeria. J Blood Disord Transfus S5: S5-004. doi:10.4172/2155-9864.1000S5-004
Copyright: © 2015 Arabi A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Factor XI deficiencies are very rare and the first case was registered among Ashkenazy Jews with two types of characteristic gene mutation. Today 152 mutations have been identified even among non-Jewish population. The present study reports the deficiency identified in a young Arabic girl living in West Algeria; gene seqensage with type II mutation was noticed in Ashkenazy Jews frequently. The present study concludes that it is happening either coincidentally or due to the constant migration history of this region.