Factor XI Deficiency in West Algeria: A Case Report and Literature Review
Arabi A*, Chekkal M, Cheref L, Bouchama S, Mehded S, Brahimi M, Yafour N and Bekadja MA
Haematology and Cell Therapy Unit, Etablissement Hospitalier et Universitaire 1er Novembre 1954 Oran, Algeria
- *Corresponding Author:
- Arabi Abdessamed
Haematology and Cell Therapy Unit
Etablissement Hospitalier et Universitaire
1er Novembre 1954 Oran, Algeria
Tel: 213 041 42 14
E-mail: [email protected]
Received date: June 08, 2015 Accepted date: July 27, 2015 Published date: July 31, 2015
Citation: Arabi A, Chekkal M, Cheref L, Bouchama S, Mehded S, et al. (2015) Factor XI Deficiency in West Algeria: A Case Report and Literature Review. J Blood Disord Transfus S4:003. doi:10.4172/2155-9864.1000S4-003
Copyright: © 2015 Arabi A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Factor XI deficiencies are rare. Initially, they were described only in Ashkenazy Jews with two types of characteristic gene mutation. Now, 152 mutations have been identified, mostly in non-Jewish population.
We report the case of a deficiency identified in Arabic young girl living in West Algeria; gene sequences showed a type II mutation, frequent in Ashkenazy Jews. May be it is coincidence; but it is possible that this finding is related to the migratory story of this region.