Factors Associated with Left Atrial Enlargement in Patients with Anemia Caused by Uterine Myoma
- *Corresponding Author:
- Min-Kyung Kang, MD, PhD
Cardiology Division, Kangnam Sacred Heart Hospital
Hallym University Medical Center, Seoul, South Korea
E-mail: [email protected]
Received date: April 11, 2016; Accepted date: July 11, 2016; Published date: July 22, 2016
Citation: Kim SH, Kang Mk, Kim HK, Chun KJ, Choi J, et al. (2016) Factors Associated with Left Atrial Enlargement in Patients with Anemia Caused by Uterine Myoma. J Clin Exp Cardiolog 7:456. doi:10.4172/2155-9880.1000456
Copyright: © 2016 Kim SH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Uterine myoma (UM) is common among female gender, and it often causes anemia. Left atrial enlargement (LAE) is commonly detected in patients with anemia as well as caused by uterine myoma. Therefore, this study was aimed to investigate the clinical implications of LAE and its associating factors in patients with anemia caused by UM.
Methods: This is a retrospective observational cross sectional study and it considered 139 female patients with UM who had undergone preoperative echocardiography. Patients were sorted into 2 groups according to the presence of LAE (n=60) or not (n=79). LAE was defined as LA volume index (LAVI) was 35 ml/m2 or more.
Results: Patients with LAE (LAVI: 41.0 ± 5.3 ml/m2) showed larger left ventricular (LV) dimension and increased LV mass index (LVMI) than patients without LAE (LAVI: 27.9 ± 3.9 ml/m2). Patients with LAE were older, showed slower heart rate (HR) and further decreased level of hemoglobin. Older age, slower HR, level of hemoglobin, larger LV, increased LMI, E/E’, right ventricular systolic pressure and decreased S’ velocity were shown to be correlated with increased LAVI. Among them, older age (OR: 1.119, 95% CI: 1.014-1.236, p=0.026) and slower HR (OR: 0.926, 95% CI: 0.878-0.977, p=0.005) were independently associated with LAE in patients with anemia caused by UM.
Conclusion: LAE was often noticed in patients with anemia caused by UM and older age and slower HR were seemed to be its associating factor.