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FDG-PET,a Complementary Modality to Computed Tomography in Radiotherapy Target Volume Delineation for Head and Neck Cancer | OMICS International | Abstract
ISSN: 2155-9619

Journal of Nuclear Medicine & Radiation Therapy
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Research Article

FDG-PET,a Complementary Modality to Computed Tomography in Radiotherapy Target Volume Delineation for Head and Neck Cancer

Voichita Bar-Ad1*, Wenyin Shi1, Madalina Tuluc2, Nitin Ohri1, David Cognetti3, Joseph Curry3 and Charles Intenso4

1Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, USA

2Department of Pathology, Thomas Jefferson University, Philadelphia, USA

3Department of Othorhynolaryngology, Thomas Jefferson University, Philadelphia, USA

4Department of Nuclear Medicine, Thomas Jefferson University, Philadelphia, USA

*Corresponding Author:
Dr. Voichita Bar-Ad
MD, Department of Radiation Oncology
Thomas Jefferson University 111 S. 11th Street
Philadelphia, PA 19107, USA
Tel:215-955-8194
E-mail: [email protected]

Received date: January 09, 2012; Accepted date: February 21, 2012; Published date: February 24, 2012

Citation: Bar-Ad V, Shi W, Tuluc M, Ohri N, Cognetti D, et al. (2012) FDG-PET, a Complementary Modality to Computed-Tomography in Radiotherapy Target Volume Delineation for Head and Neck Cancer. J Nucl Med Radiat Ther 3:124. doi: 10.4172/2155-9619.1000124

Copyright: © 2012 Bar-Ad V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objectives: The objective of the current review was to use published data to assess the role of [18F] fluorodeoxyglucose-positron emission tomography (FDG-PET) as a complementary modality to computedtomography (CT) in radiotherapy target volume delineation for head and neck cancer (HNC).

Methods: Studies were identified by searching PubMed electronic databases. Both prospective and retrospective studies were included. Information regarding the role of FDG-PET for radiotherapy target volume delineation for HNC was analyzed.

Results: FDG-PET is a promising tool for improving radiotherapy target volume delineation by defining a metabolically active biological target volume (BTV). The use of novel PET tracers representing properties such as hypoxia, protein synthesis and proliferation remain to be better characterized.

Conclusions: The role of FDG-PET for radiotherapy target volume delineation for patients with HNC is expanding and should be further evaluated in clinical trials.

Keywords

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