alexa Fermented Medicinal Plant Designed by Lactobacillus Hits Alternative Complement Pathway and Controlled hA1c Level | OMICS International | Abstract
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Fermented Medicinal Plant Designed by Lactobacillus Hits Alternative Complement Pathway and Controlled hA1c Level

Yamaguchi N1,2*, Akazawa-Kudoh S3, Sawada M3, Fujimoto Y3 and Murayama T4

1Ishikawa Natural Medicinal Products Research Center, Ishikawa, Japan

2Department of Fundament Research for CAM, Kanazawa Medical University, Ishikawa, Japan

3Department of General Medicine, Kanazawa Medical University, Ishikawa, Japan

4Department of Microbiology and Immunology, Faculty of Pharmaceutical Sciences, Hokuriku University, Ishikawa, 920-1181, Japan

*Corresponding Author:
Nobuo Yamaguchi
Ishikawa Natural Medicinal Products
Research Center, Ishikawa, Japan
Tel: +817622258852
E-mail: [email protected]

Received date: March 21, 2017; Accepted date: March 31, 2017; Published date: April 05, 2017

Citation: Yamaguchi N, Akazawa-Kudoh S, Sawada M, Fujimoto Y, Murayama T (2017) Fermented Medicinal Plant Designed by Lactobacillus Hits Alternative Complement Pathway and Controlled hA1c Level. Nat Prod Chem Res 5:260. doi:10.4172/2329-6836.1000260

Copyright: © 2017 Yamaguchi N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: A Type II Diabetes mellitus showed many symptoms that brought serious for the patients. One of the problem was suppressed activity of the phagocyte for the foreign microorganism.

Objective: The objective of this study was to find excellent method to recover the suppressed phagocytic cell activity both in animal and human.

Methods: A wild medicinal herbs were prepared by Yeast and Lactobaccilli against 80 sorts of wild plants including medicinal remedies (FWP80). These products were exhibited by safe in animal safety test. The trial was made to investigate a recovery of immune-competent cells both in mice and human that exhibited phagocytic depression.

Results: Our results in animal model showed that FWP80 augmented the macrophage activity, both chemotaxis and phagocytosis. In clinical study with 20 volunteers diagnosed type II DM, the granulocyte and lymphocyte ratio was produced to as modulate as neutral, 30 days after the introduction by FWP80.

Conclusion: In mice, depressed phagocytic cell by Streptozotocin, the macrophage activities were recovered by FWP80. We proposed an idea that FWP80 exhibited remedy effect via controlling complement component. The mechanism of activation was proved by activating alternative pathway of complement by the technic, immuneelectrophoresis. We tried to evaluate more to the anti-oxidative activities of FWP80, directory employing peritoneal macrophage in vivo.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7