Fibrin Sealant and Femtosecond Laser Assisted Keratoplasty: Initial Results
- *Corresponding Author:
- Tatiana Prazeres MB
Rua Conselheiro Correa de Menezes, n266
Apt 701, Salvador, Bahia, Brazil
Tel: 55-71-3334-3084/ 55-71-8799-3084
E-mail: [email protected]
Received Date: January 26, 2012; Accepted Date: July 12, 2012; Published Date: July 14, 2012
Citation: Prazeres TMB, Lindoso EMS, Grupenmacher L, Sousa LB (2012) Fibrin Sealant and Femtosecond Laser Assisted Keratoplasty: Initial Results. J Transplant Technol Res 2: 112. doi: 10.4172/2161-0991.1000112
Copyright: © 2012 Prazeres TMB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Purpose: To evaluate whether the use of a sealant combined with interrupted suture would provide better visual outcomes and better post-operative recovery to keratoconic patients compared to interrupt and running sutures without the use of sealants using femtosecond laser assisted keratoplasty.
Methods: A prospective, randomized study of 12 patients (12 eyes) with keratoconus was conducted, randomized into two treatment groups. The no glue group (6 eyes) underwent penetrated keratoplasty (PK) with femtosecond laser assisted keratoplasty shaped (mushroom) and combined suture (8 interrupted suture and 8 running sutures) while the glue group (6 eyes) underwent the same procedure but their incisions were closed with 8 interrupted sutures and sealant.
Results: The no glue group had a mean BCVA of 0.2 (LogMar). The glue group had a mean BCVA of 0. (LogMar). p=0.028 Transplants with glue were well positioned showing good healing but presented more inflammation in the first week post-surgery. Regarding refractive outcomes, there was no difference between the groups.
Conclusions: There were no statistical difference between the two groups regarding BCVA and refractive errors. The use of sealants produced more inflammation. Further studies with a larger number of patients and longer follow up would be needed to confirm these findings.