Field Application of a Combined Vaccine against Peste Des Petits Ruminants and Sheep Pox
- *Corresponding Author:
- Fakri F
Multi-Chemical Industry, Lot. 157, Z I
Sud-Ouest (ERAC) B.P: 278, Mohammedia, Morocco
E-mail: [email protected]
Received date: October 26, 2015 Accepted date: November 20, 2015 Published date: November 25, 2015
Citation: Fakri F, Ghzal F, Daouam S, Elarkam A, Douieb L, et al. (2015) Field Application of a Combined Vaccine against Peste Des Petits Ruminants and Sheep Pox. J Vaccines Vaccin 6:301. doi: 10.4172/2157-7560.1000301
Copyright: © 2015 Fakri F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A combined vaccine against peste des petits ruminants (PPR) and sheep/goat pox (SGP), based on Nigeria 75 PPR strain and sheep pox Romania strain, was developed and applied in the field. Safety and efficacy were evaluated on goats and sheep in comparison with monovalent PPR and SGP vaccines. Goats were challenged by PPR virulent strain and sheep by SP virulent strain. The result showsthat the combined PPR/SGP vaccine confers a good protection against both PPR and SGP infection with no significant difference with monovalent vaccines. The combined vaccine was used in Morocco and other African countries on small ruminant flocks with good safety and satisfactory sero-conversion detected against both PPR and SGP viruses, as soon as 14 days post vaccination. It’s the first time where a combined vaccine was applied in large vaccination campaigns to prevent in one shot the two diseases.